Waters ACQUITY Premier Columns: A New Solution for Sample Loss of Metal-Sensitive Analytes

Waters ACQUITY Premier Columns: A New Solution for Sample Loss of Metal-Sensitive Analytes

Why do we lose compounds while trying to measure them? Are they disappearing? Are they breaking down? Why and how? It all starts with adsorption and for certain metal-sensitive analytes, it renders chromatographic analysis using stainless steel columns a significant chore. Thankfully, Waters engineers have created an elegant solution to this widely experienced, yet lesser…

Chords and Chemistry and the Benefits of Choosing Wisely

Chords and Chemistry and the Benefits of Choosing Wisely

“A true measure of excellence for Waters is in orchestrating consistent instrument and chemistry optimization across applications, methods, and workflows.” I was on a job interview – more specifically, for my first position at Waters – where I was asked a compelling question. The question had to do with the consideration that Waters was a…

In Need of Some Reversed Phase Polar Acid Relief

In Need of Some Reversed Phase Polar Acid Relief

Retaining polar analytes using reversed phase (RP) chromatographic conditions have long frustrated scientists.  Trying to promote interactions between polar analytes and a non-polar reversed phase surfaces can often bring the most experienced separation scientist to their breaking point. Polar acids specifically present their own set of challenges that make them particularly difficult to retain under…

Bring efficiency back to your lab: How aging technology hinders ideal performance

Bring efficiency back to your lab: How aging technology hinders ideal performance

In this series, we review considerations for keeping your lab at the forefront of science. As we adjust to living and working in a pandemic and anticipate future global and geopolitical events, Waters remains dedicated to supporting your business and unlocking the potential of your science. Our holistic separations solutions and expert support help you…

Addressing the Mystery of Sample Loss

Addressing the Mystery of Sample Loss

Many years ago, I was hired by a biopharma company to develop analytical methods for therapeutic oligonucleotides. When a new colleague warned me about sample loss on LC columns I looked at him with skepticism. “Yes,” he insisted, “part of your DNA sample may be irreversibly bound to the column and you will never see…

Change Up Your Routine (Analysis)

Change Up Your Routine (Analysis)

Enhancing performance, mitigating risk, and improving efficiency Today, Waters introduced the Arc HPLC, a modern liquid chromatography system that replicates established test methods while delivering improved performance. HPLC has been a cornerstone of routine analytical testing for decades. It has proven to be particularly important for quality control and manufacturing support laboratories in the pharmaceutical…

Reveal Molecular Secrets – and Set Them to Work!

Reveal Molecular Secrets – and Set Them to Work!

From fundamental research to routine analysis, Waters’ latest innovations in mass spectrometry enable our customers to gain – and apply – insights across the scientific spectrum. Beginning with fundamental research where the focus is on unraveling molecular complexity, new enhancements to the SELECT SERIES™ Cyclic IMS now support a combination of fragmentation and imaging strategies…

Setting a New Bar for Benchtop Automation

Setting a New Bar for Benchtop Automation

Laboratory automation is quickly becoming a critical component of the modern lab, streamlining pharmaceutical, life science and analytical LC-MS workflows.  Automation of routine and complex sample preparation helps minimize variability, improve traceability and simplify method transfer, ultimately bringing improved efficiency to the lab and allowing scientists to spend more time on value-added tasks. Despite this,…

Waters and the University of Tokyo Collaborate on Lipidomics Research

Waters and the University of Tokyo Collaborate on Lipidomics Research

Digging deep into the human biome, Professor Yoshiya Oda of the Graduate School of Medicine at the University of Tokyo looks to ion mobility technology to uncover deposits of insight It’s an established fact that the more people age, the more they tend to engage with health care providers than they did when they were…

The University of Neuchâtel Selects the SYNAPT™ XS to Enable Future Discoveries in Plant Metabolomics

The University of Neuchâtel Selects the SYNAPT™ XS to Enable Future Discoveries in Plant Metabolomics

After a comprehensive evaluation process, The University of Neuchâtel in Switzerland recently made the decision to add the newly released SYNAPT XS to their mass spectrometry instrument portfolio. Dr. Gaétan Glauser, a senior scientist at the Neuchâtel Platform of Analytical Chemistry (NPAC) facility, has core specialisms in plant analytical chemistry and metabolomics. Dr. Glauser and…

Learning from User Experience

Learning from User Experience

What does “intelligence” mean in the context of biopharma analysis? Given the complex setting, much of the answer comes down to the task a user needs to complete, along with the question of who exactly that user is. In developing our BioAccord System, we wanted to expand the possibilities of high-resolution LC-MS analysis from characterization…

Amgen, UCLA, and University of Arizona Use BioResolve RP mAb Polyphenyl Columns for Rapid LC-MS Screening of Membrane Proteins

Amgen, UCLA, and University of Arizona Use BioResolve RP mAb Polyphenyl Columns for Rapid LC-MS Screening of Membrane Proteins

As a chromatography scientist at Waters, I often get the opportunity to travel to different laboratories around the world and to meet with various types of researchers. This allows me to stay up to date on the newest scientific trends and topics, particularly in the fast growing world of biopharmaceutical analysis. In June of this…