ACQUITY UPLC I-Class/Xevo TQ-S micro IVD System
Reproducible quantitative data that transforms testing into better care
Consistently achieving low levels of quantitation with a wide dynamic range is a challenge, especially when your clinical laboratory doesn’t have space for a large instrument. Waters ACQUITY UPLC I-Class/Xevo TQ-S micro IVD System delivers ultra-high performance for consistent and accurate low-concentration quantification, all in a compact design.
With LC-MS/MS analysis, your lab can achieve selectivity, sensitivity, and functional versatility unmatched by traditional techniques for analyzing complex bioliquid samples. With its compact design, Xtended Dynamic Range (XDR) detector, and innovative tandem quadrupole mass spectrometry, the Waters ACQUITY UPLC I-Class/Xevo TQ-S micro IVD System is ideal for small spaces and big sample challenges.
ACQUITY UPLC I-Class/Xevo TQ-S micro IVD System
Overview
- Achieve reproducible, robust detection of analytes at low levels in complex bioliquid sample matrices using a compact system
- Quantify more analytes accurately, quickly, and reliably with high acquisition rates
- Get sensitivity and optimal method transfer with Waters Xtended Dynamic Range (XDR) Detector
- Optimize method development and fully understand complex samples using Waters RADAR technology
- Access the selectivity, sensitivity, and versatility of LC-MS/MS analysis in the clinical laboratory
- Adhere to relevant international quality standards for medical devices using Waters LC-MS/MS IVD systems
Recommended Use: Ideal for low concentration analyte quantification in the clinical lab environment.
Reliable IVD performance in a powerful compact design
Reliable performance from the ZSpray geometry in ACQUITY UPLC I-Class/Xevo TQ-S micro IVD System effectively removes neutral molecules while drawing ions into the mass spectrometer through the sample cone. The Xevo TQ-S micro features Waters StepWave ion guide to meet the challenges of high sample throughput and complex matrices in modern clinical labs.
The ACQUITY UPLC I-Class/Xevo TQ-S micro IVD System passively removes neutrals and gas load and enhances transmission, while ions are actively transported into the mass analyzer for improved sensitivity and robustness. The Xevo TQ-S micro features a leading compact design with an extremely small footprint and full functionality.
Faster data point acquisition under high sensitivity conditions
Acquire data at extremely high speeds without compromising performance with the Xccelerated Ion Transfer (XIT) electronics with SpaceWire technology in ACQUITY UPLC I-Class/Xevo TQ-S micro IVD System. The next-generation T-Wave collision cell can acquire 500 multiple reaction monitoring (MRM) channels per second while significantly reducing cross-talk and maintaining unaffected intensity. The enhanced MS full scan speed capability (up to 20,000 Da/s) reduces the impact on the duty cycle when switching quickly between MS full scan and MS/MS acquisition modes (RADAR and PICs).
Additionally, the fast polarity switching enables full coverage of positive and negative ionized compounds in a single injection. Maintaining performance at such speeds is especially important because every clinical lab needs reproducible, high-quality data for reliable quantification. You can make method transfer even easier with the advanced Xtended Dynamic Range (XDR) detector, which uses the unique XDR technology to improve usability at low detection limits.
Fully understand sample complexity in clinical LC-MS/MS method development
With RADAR technology, you can acquire both full scan (MS) and MRM (MS/MS) data simultaneously, enabling you to overcome significant quantitative methods challenges. Now your lab can efficiently perform targeted analysis for analytes of interest and detect unexpected analytes in the same injection. You can improve data quality by performing background matrix characterization for every sample in each run, and examine matrix background during method development to better characterize target methods for interferences and ion-enhanced and ion-suppressed species.
Comprehensive data processing with simple result review
The ability to access and rapidly review quantitative data is essential for any clinical lab. With the TargetLynx XS Application Manager, your lab can readily access and review the data you need and get the ability to accurately calculate analyte concentrations through standard addition. Built on years of iterative design, the TargetLynx XS Application Manager helps your lab achieve an efficient workflow for rapid data review and reporting – so you can be sure your results reach their destination as smoothly and quickly as possible.
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