• Note d'application

Omeprazole in Rat Plasma

Omeprazole in Rat Plasma
  • Waters Corporation
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This is an Application Brief and does not contain a detailed Experimental section.

Abstract

This application brief highlights the anlysis of omeprazole using XTerra MS C18 columns.

Introduction

Omeprazole in rat plasma has been analyzed in this study.

Experimental

HPLC Conditions

Column:

XTerra MS C18 2.1 x 30 mm, 3.5 μm (p/n: 186000398)

Mobile phase A:

1.0% NH4OH

Mobile phase B:

ACN

Isocratic mobile phase composition:

50% A; 50% B

Flow rate:

0.2 mL/min

Injection volume:

20 μL

Detection:

MS ESI+

Instrument:

Alliance 2690, Micromass Quattro Ultima

MS Conditions

Ion source:

ESI+

Source temp.:

150 °C

Gas cell:

1.5e-3 mbar, 10 eV

Desolvation temp.:

350 °C

Cone gas flow:

150 L/hr

Drying gas flow:

600 L/hr

Cone voltage:

30 V

Results and Discussion

Featured Products

WA20738.082, June 2002

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