Preparo de amostras simplificado. Desenvolvimento robusto de métodos.
Atenda às necessidades específicas do seu laboratório e ao nível de sensibilidade e produtividade desejados com as soluções inovadoras de preparo de amostras da Waters. Acelere e simplifique o cleanup da matriz de amostras, aumente a concentração de amostras com melhor sensibilidade e encare qualquer outro desafio de preparo de amostras com o portfólio de soluções abrangente e variado da Waters, desenvolvido com base em anos de experiência analítica prática.
Development of an LC–MS/MS assay for quantification of intact INSL3 in rat plasma
— Nicole A Schneck; Lela Mortezavi; Alan R Olzinski, Diane Posavec; Larry J Jolivette, Timothy W Sikorski; Shan-Shan Zhang; Christine G Schnackenberg; Hermes Licea-Perez. Bioanalysis.
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Optimisation of Solid-Phase Extraction and LC-MS/MS Analysis of Six Breast Cancer Drugs in Patient Plasma Samples
— Lu Turković; Dragana Mutavdžić Pavlović; Zvonimir Mlinarić; Anamarija Skenderović; Tajana Silovski Miranda Sertić. Journal of Chromatographic Science.
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Comparison of Reversed-Phase and Mixed-Mode SPE for Enrichment and Clean-Up of Surrogate Peptides in CysC Quantified by LC–MS/MS
— Zijie Tang; Huoyan Ji. Journal of Chromatographic Science.
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Development and Validation of an HILIC/MS/MS Method for Determination of Nusinersen in Rabbit Plasma
— Zhang, X.; Sha, C.; Zhang, W.; Zhao, F.; Zhu, M.; Leng, G.; Liu, W. Heliyon 2024, 10(10), e31213.
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Innovative Solid-Phase Extraction Strategies for Improving the Advanced Chromatographic Determination of Drugs in Challenging Biological Samples
— Mahdavijalal, M.; Petio, C.; Staffilano, G.; Mandrioli, R.; Protti, M. Biological Samples. Molecules 2024, 29(10), 2278.
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Optimizing Solid Phase Extraction and HPLC-MS/MS Parameters for Reliable Quantification of COVID-19 Pharmaceuticals in Mexico City’s Wastewater: A Design of Experiments Approach
— Cortés-Lagunes, R. S.; Garduño-Jiménez, A.-L.; Romero-Solano, A.; Zanella, R.; Prado, B.; Zamora, O.; Durán-Álvarez, J. C. Microchem. J. 2024, 190, e108936.
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Development and validation of a simple, selective, and sensitive LC-MS/MS assay for the quantification of remdesivir in human plasma
— Ryan Nguyen; Jennifer C. Goodell; Priya S.Shankarappa; Sara Zimmerman; Tyler Yin; Cody J. Peer; William D. Figg. Journal of Chromatography B.
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Simultaneous determination of fluoxetine, venlafaxine, vortioxetine and their active metabolites in human plasma by LC–MS/MS using one-step sample preparation procedure
— Martin Kertys; Michaela Krivosova; Igor Ondrejka; Igor Hrtanek; Ingrid Tonhajzerova. Journal of Pharmaceutical and Biomedical Analysis.
DOI: 10.1016/j.jpba.2020.113098.
Integrative phosphatidylcholine metabolism through phospholipase A2 in rats with chronic kidney disease
— Yan-ni Wang; Zhi-hao Zhang; Hong-jiao Liu; Zhi-yuan Guo; Liang Zou; Ya-mei Zhang; Ying-yong Zhao. Acta Pharmacologica Sinica, 44, 393–405 (2023).
Associations of Cord Plasma Per- and Polyfluoroalkyl Substances (PFAS) with Neonatal and Child Body Composition and Adiposity: The GUSTO Study
— Chen, L.-W.; Ng, S.; Tint, M.-T.; Michael, N.; Sadananthan, S. A.; Ong, Y. Y.; Yuan, W. L.; Chen, Z.-Y.; Chen, C.-Y.; Godfrey, K. M.; Tan, K. H.; Gluckman, P. D.; Chong, Y.-S.; Eriksson, J. G.; Yap, F.; Lee, Y. S.; Fortier, M. V.; Velan, S. S.; Chan. Environ. Int. 2024.
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Quantitative Determination of R/S-Methadone in Human Serum Using Ultra-High Performance Supercritical Fluid Chromatography-Tandem Mass Spectrometry: A Method for Routine Use
— Hansen, M.; Havnen, H.; Andreassen, T. N.; Spigset, O.; Hegstad, S. Drug Test. Anal. 2024.
DOI: 10.1002/dta.3693
Moxidectin is a candidate for use as an in vivo internal standard in pharmacokinetic studies, as demonstrated with use in simultaneous tissue cage and ultrafiltration fluid collection
— Munn, R.; Whittem, T. Front. Vet. Sci. 2024, 11.
DOI: 10.3389/fvets.2024.1332974.
Topical Wound Treatment with a Nitric Oxide-Releasing PDE5 Inhibitor Formulation Enhances Blood Perfusion and Promotes Healing in Mice
— Maya Ben-Yehuda Greenwald; Yu-Hang Liu; Weiye Li;Paul Hiebert; Maria Zubair; Hermann Tenor; Tobias Braun; Reto Naef; Daniel Razansky; Sabine Werner. Pharmaceutics 2022, 14(11), 2358.
DOI: 10.3390/pharmaceutics14112358.
Sample preparation strategies for mass spectrometry analysis in human exposome research: Current status and future perspectives
— Yunyun Gu; Jesse T. Peach; Benedikt Warth. TrAC Trends in Analytical Chemistry.
DOI: 10.1016/j.trac.2023.117151.
Pharmacodynamics of Tebipenem: New Options for Oral Treatment of Multidrug-Resistant Gram-Negative Infections
— Laura McEntee; Adam Johnson; Nicola Farrington; Jennifer Unsworth; Aaron Dane; Akash Jain; Nicole Cotroneo; Ian Critchley; David Melnick; Thomas Parr; Paul G. Ambrose; Shampa Das; William Hope. ASM Journals.
DOI: 10.1128/aac.00603-19.
Targeted and untargeted metabolomic profiles in wild rabbit does (Oryctolagus cuniculus) of different breeding states (pregnant and lactating)
— Marín-García, P. J.; Rouco, C.; Llobat, L.; Larsen, T.; Hedemann, M. S. J. Exp. Zool. A 2024.
DOI: 10.1002/jez.2818
Preclinical Testing of Chronic ICA-1S Exposure: A Potent Protein Kinase C-ι Inhibitor as a Potential Carcinoma Therapeutic
— Apostolatos, C. A.; Ratnayake, W. S.; Breedy, S.; Chuah, J. K. C.; Miller, J. A.; Zink, D.; Bourgeois, M.; Acevedo-Duncan, M. Drugs Drug Candidates 2024, 3(2), 368–379.
DOI: 10.3390/ddc3020022.
Role of Glucose Metabolism Reprogramming in Keratinocytes in the Link between Psoriasis and Metabolic Syndrome
—Yan, L.; Wang, W.; Qiu, Y.; Yu, C.; Wang, R.; Li, C. Int. Immunopharmacol. 2024, 112, 112704.
DOI: 10.1016/j.intimp.2024.112704.