• Note d'application

Sulfa Drugs in Serum (Antibacterial)

Sulfa Drugs in Serum (Antibacterial)
  • Waters Corporation
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This is an Application Brief and does not contain a detailed Experimental section.

Abstract

This application brief demonstrates analysis of sulfa drugs in serum.

Introduction

The compounds used in this study are –

  1. Sulfadiazine
  2. Sulfathiazole (I.S.)
  3. Sulfamerazine

Experimental

HPLC Method

Column:

Symmetry C18, 3.9 x 150 mm, 5 μm

Part number:

WAT046980

Mobile phase:

1% glacial acetic acid and 4% methanol in water

Flow rate:

1 mL/min

Injection volume:

10 μL of reconstituted porcine serum extract

Temperature:

25 °C

Detection:

UV @ 254 nm

Results and Discussion

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WA31764.142, June 2003

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