Advancements in chemical library synthesis, fractional drug design, and AI modeling have resulted in a greater number and variety of compounds requiring evaluation in drug discovery, but selecting the best compounds to take forward requires rapid determination of their physical chemistry and in vitro DMPK properties. Automated mass spectrometry (MS) method generation and high-throughput LC-MS analysis are critical to successfully supporting these studies.
With Waters In Vitro ADME Solutions, including ACQUITY Premier System with optional Open Architecture CTC PaL autosampler configuration, Xevo TQ-S micro Tandem Quad Mass Spectrometer, and MassLynx QuanOptimize Software, your lab can automate MS method development through to data analysis and reporting, in order to optimize discovery ADME productivity.
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