HPLC Columns
HPLC Columns
Create exceptional chromatography and achieve repeatable results with Waters high performance liquid chromatography (HPLC) columns.
Create exceptional chromatography and achieve repeatable results with Waters high performance liquid chromatography (HPLC) columns.

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Resolve your toughest separation challenges with Waters analytical and preparative HPLC columns, which come in 5,800+ column formats, 175+ column configurations, and 21 unique column phases — for excellent performance and column-to-column reproducibility.
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- CORTECS Premier ColumnsEliminate doubt in UPLC, UHPLC, and HPLC analysis applications with CORTECS Premier Columns, designed to increase sample throughput while providing reproducible data for all analytes.
- XSelect Premier ColumnsDiscover XSelect Premier UHPLC Columns designed to improve peak shape and maximize selectivity while mitigating unwanted analyte/surface interactions.
- CORTECS ColumnsMaximize resolution and peak capacity for LC separations with CORTECS solid-core columns in 1.6 and 2.7 µm across 7 column chemistries.
- XBridge ColumnsExperience XBridge HPLC and UHPLC Columns, ideal for methods development at extreme temperatures and mobile-phase pH. Explore XBridge BEH Column chemistries today.
- Atlantis ColumnsImprove chromatographic performance, retention, and stability for polar compounds with Atlantis HPLC Columns. Discover Atlantis C18 and HILIC column chemistries now.
- XSelect ColumnsGet superior selectivity and peak shape for basic compounds with XSelect HPLC and UHPLC Columns. Discover our CSH and high-strength silica columns. Visit today.
- Advanced Purification Glass ColumnsMeet protein purification needs with Advanced Purification glass columns with silica, polymer or soft gel packings, designed for analytical & preparative LC instruments.
- BioResolve ColumnsStreamline analytical challenges associated with mAb characterizations and associated biotherapeutic drug separations with BioResolve Columns.
- BioResolve Premier ColumnsIncrease bioanalysis recovery, reproducibility, and enhance LC and LC-MS sensitivity with Waters BioResolve Premier Columns, reversed-phase ion exchange columns designed for bioanalysis applications
- BioSuite ColumnsIdeal for the isolation, analysis, and characterization of proteins and peptides, BioSuite Columns offer multiple chemistries: C18, cation and anion-exchange, SEC, & Phenyl.
- Delta-Pak ColumnsSeparate and isolate peptides, proteins, and natural products with Delta-Pak HPLC Columns for large molecule separations.
- GTxResolve SEC ColumnsReliable and robust critical quality attribute analysis of aggregates for Lipids nanoparticles (LNPs), nucleic acids, and viral vectors using GTxResolve columns.
- MaxPeak Premier OBD Preparative ColumnsMinimize non-specific adsorption (NSA) inherent to preparative chromatography while yielding high-purity results with MaxPeak Premier OBD Preparative Columns.
- Nova-Pak ColumnsGet higher resolution and efficiency for HPLC with Nova-Pak analytical and semi-preparative columns. Discover Nova-Pak C18, C8, Cyano & Phenyl column chemistries.
- Protein-Pak ColumnsAchieve high-quality LC-based analyses & lab scale purifications of peptides and proteins with Protein-Pak IEX & HIC Columns, designed for use on HPLC and UPLC systems.
- Resolve ColumnsAchieve high retention and high resolution of polar compounds with non-endcapped Resolve Columns available in C18, C8 and Cyano column chemistries.
- Shodex RSpak ColumnsPolymeric reversed-phase columns for basic compounds and applications requiring a broad pH range (2–12). Shodex RSpak Columns chemistries include DE-613 and DS-613.
- SunFire ColumnsGet exceptionally high mass loading for both analytical and preparative columns with SunFire HPLC Columns. Discover SunFire Silica, C8, and C18 columns.
- Symmetry HPLC ColumnsGet predictable analytical performance and ensure batch-to-batch reproducibility with high purity silica-based Symmetry HPLC Columns.
- VanGuard Column ProtectionSafeguard analytical HPLC, UHPLC, and UPLC columns from the effects of damaging particulates and chemical contaminates with VanGuard Cartridges and Pre-columns.
- Waters Insulin HMWP ColumnAnalyze insulin products for impurities with Waters Insulin HMWP Gel Filtration HPLC Columns. Learn about insulin gel filtration column packing now.
- Waters PAH ColumnsGet superior peak identification and quantitation for Polyaromatic Hydrocarbons (PAHs) compounds with Waters PAH C18 HPLC Columns.
- Waters Spherisorb HPLC ColumnsDiscover unique separation selectivities with Waters Spherisorb Columns, the most widely referenced products for analytical and preparative column chromatography.
- XBridge Premier ColumnsExperience XBridge Premier UHPLC Columns, designed to operate under extreme temperatures and mobile-phase pH while mitigating unwanted analyte/surface interactions.
- XTerra ColumnsPerform low and high pH drug discovery, method development and purification separations with XTerra hybrid particle technology HPLC columns. Learn more.
- µBondapak and Bondapak ColumnsSeparate acidic, basic, and neutral compounds with µBondaPak and BondaPak Columns. These HPLC columns are available in phenyl, C18, cyano and NH2 column chemistries.
- µPorasil/Porasil ColumnsGet reliable normal-phase chromatography separations with non-bonded, silica-based μPorasil and Porasil Columns. Research µPorasil/Porasil HPLC Column options.