Emerging Contaminant of Concern - Perfluorinated Compounds (PFOS/PFOA)

Recent research has provided evidence that perfluorinated compounds (PFCs), such as perfluorooctanesulfonic acid (PFOS) and perfluorooctanoic acid (PFOA), are persistant organic pollutants and are ubiquitous in the environment.

Benefits

Analytical method for perfluorinated compounds (PFCs)

Recent research has provided evidence that perfluorinated com-pounds (PFCs), such as perfluorooctanesulfonic acid (PFOS) and per-fluorooctanoic acid (PFOA), are persistant organic pollutants and are ubiquitous in the environment. Because PFCs may be toxic and have bioaccumulative properties, there is growing interest in the develop-ment of analytical methods for PFCs in the environment.

Sample preparation

Method 1: Water

Water samples [100 mL] were spiked with the appropriate com-pounds, adjusted to pH 3 with formic acid, and then processed by SPE. The SPE eluate [Elute 2] was collected in polypropylene test tubes, diluted with 2 mL of 2% aqueous formic acid and brought to 5 mL with water. Alternatively, the eluate may be evaporated and reconstituted in mobile phase prior to analysis, but polypropylene labware should be used exclusively.

Method 2: Tissues

A 1 mL aliquot of supernatant was diluted to 20 mL with water and the pH was adjusted to 4–5 using 2% formic acid. This solution was then loaded on an Oasis WAX cartridge. SPE eluates were evapo-rated and reconstituted in 1 mL of mobile phase [polypropylene labware].

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