Translating biomarker discoveries into practical, quantitative assays can be complex, requiring considerations for throughput, reproducibility, scalability, and sensitivity. As demand grows for targeted assays in proteomics, metabolomics, and lipidomics, method development, and implementation become increasingly time-intensive and challenging.
Waters streamlines targeted omics analysis with innovative LC-MS/MS solutions that enhance your laboratory’s biomarker quantification with precision and accuracy, accelerating results, and improving efficiency. The Waters Targeted Omics Library offers ready-to-use, downloadable methods, reducing development time, and enabling your lab to stay ahead in biomarker discovery—without overextending your resources. With Waters, you can:
Expand your analytical capabilities with the versatile Xevo TQ-Absolute that offers superior performance for your quantitative workflows.
Obtain superior performance in routine quantitation, exceptional analytical flexibility, and outstanding sensitivity with the Xevo TQ-S micro that can reproduce high quality analytical performance injection after injection, even with the most complex sample matrices.
Enhance the quantitative performance of your LC-MS/MS assay and minimize the impact of non-specific binding with Waters ACQUITY Premier UPLC System.
Integrate microflow UPLC directly into the source of the mass spectrometer with the ionKey/MS System for an increased level of sensitivity, chromatographic performance, and ease-of-use in targeted proteomics assays.
Achieve the sensitivity of micro- and nanoflow liquid chromatography with UPLC technology with the ACQUITY UPLC M-Class System, accommodating overflow rates from 200 nL/min to 100 µL/min and column inner diameters (I.D.) from 75 µm to 1.0 mm.
Overlay of extracted MRM chromatograms for each of the light and heavy stable isotope labeled peptides in the mixture for a 0.5 μL injection in the presence of E. coli background matrix. Red indicates the light and blue the heavy labeled analogue.
Variation in bile acid abundance following dosing with methapyrilene at 50 and 150 mg/kg in Rodent Toxicology Study.
Quantitative measurement consistency for peptide AVQQPDGLAVLGIFLK, where brown indicates the light peptide analogue analyzed by ionKey/MS System.
Negative ion mode chromatogram representing HILIC separation of different lipid classes in plasma. The inset chromatogram shows a zoom of the different lipid classes.
