Amino Acids Testing

Amino Acids Testing

Accurately separate, identify, and quantify free or protein-bound amino acids with Waters amino acid testing solutions. With Waters solutions, support, and expertise, your lab can successfully monitor and optimize processes to confirm nutritional composition analysis and manufacturing specifications for food, feeds, and beverage products.

Accurately separate, identify, and quantify free or protein-bound amino acids with Waters amino acid testing solutions. With Waters solutions, support, and expertise, your lab can successfully monitor and optimize processes to confirm nutritional composition analysis and manufacturing specifications for food, feeds, and beverage products.

Foods rich in amino acids
Foods rich in amino acids

Overview

Amino acid analysis presents unique challenges compared to other food components testing, requiring simultaneous analysis of nearly 20 amino acids in a single analysis. This necessitates exceptional chromatographic resolution and specificity to achieve accurate and reproducible results. Waters amino acid analysis solutions include:

  •  AccQ•Tag (Ultra) Derivatization Reagents Fit: With more than 15 years of proven performance, these easy-to-use reagents, along with our quality-control tested columns and eluents, ensure accuracy and reproducibility of results.
  • Robust HPLC and UHPLC Systems: Coupled with UV and FLR detectors, these systems offer superior chromatographic resolution and maximum sensitivity detection.
  • Empower Software: Comes with pre-configured projects, methods and report formats, streamlining your analytical processes.

Applications

Waters solutions enable accurate quantification of amino acids across various food sample types including infant formula and dietary supplements. These robust solutions adapt seamlessly to different LC system configurations without compromising the performance.

Waters solutions enable accurate quantification of amino acids across various food sample types including infant formula and dietary supplements. These robust solutions adapt seamlessly to different LC system configurations without compromising the performance.


Amino acid analysis can be performed with or without pre-derivatization, using various column chemistries. Even with mass spectrometry, pre-derivatization with AccQ-Tag proves valuable in improving method specificity, selectivity, and sensitivity.

Amino acid analysis can be performed with or without pre-derivatization, using various column chemistries. Even with mass spectrometry, pre-derivatization with AccQ-Tag proves valuable in improving method specificity, selectivity, and sensitivity.


Discover how Waters Andrew+ liquid handling robot with the AccQ●Tag Ultra Derivatization Automation Kit can transform your sample preparation. By automating routine tasks, it not only ensures consistent and robust results, but also frees up your time to focus on more value-added activities.

Discover how Waters Andrew+ liquid handling robot with the AccQ●Tag Ultra Derivatization Automation Kit can transform your sample preparation. By automating routine tasks, it not only ensures consistent and robust results, but also frees up your time to focus on more value-added activities.




Primer: A Comprehensive Guide to Hydrolysis and Analysis of Amino Acids

Accurately separating, identifying, and quantitating amino acids in food, feed, and biotherapeutics is challenging. Common to these applications is the need for adequate sample hydrolysis, an important first step. This primer compiles useful hints and tips for sample hydrolysis for those performing amino acid analysis and experienced analysts trying to resolve a related issue.

Accurately separating, identifying, and quantitating amino acids in food, feed, and biotherapeutics is challenging. Common to these applications is the need for adequate sample hydrolysis, an important first step. This primer compiles useful hints and tips for sample hydrolysis for those performing amino acid analysis and experienced analysts trying to resolve a related issue.


Amino Acid illustration

Solutions


Enhance efficiency and accelerate sample throughput with solutions tailored to labs conducting amino acid analysis for food and feeds.

Enhance efficiency and accelerate sample throughput with solutions tailored to labs conducting amino acid analysis for food and feeds.

The next evolution in separation science is here

The next evolution in separation science is here

Maximize the sensitivity, repeatability, and robustness of your LC and LC-MS applications with the ACQUITY Premier System that features MaxPeak High Performance Surfaces (HPS) Technology for improvements in the separation and detection of metal-sensitive analytes.

  • UV Methods
  • MS Methods
  • Automation

See clearly and consistently, with confidence

See clearly and consistently, with confidence

Reduce non-specific adsorption from metal interactions in HPLC and UHPLC applications and obtain higher quality data with the Arc Premier System that produces correct, robust results from the very first injection, reliably, and easily.

  • UV Methods
  • MS Methods
  • Automation

Highly reliable, low complexity, accurate routine analysis for all

Highly reliable, low complexity, accurate routine analysis for all

Count on high-efficiency separations and quality data to meet your regulatory requirements with the Arc HPLC System and easily improve the performance of your existing LC methods for right-the-first-time analysis.

  • UV Methods
  • MS Methods
  • Automation

A new era of intuitive simplicity

A new era of intuitive simplicity

Reduce human errors, HPLC system downtime, enhance productivity and generate consistent, repeatable global method performance with the Alliance iS System that offers intuitive touchscreen tools that stop unacceptable runs before they occur.

  • UV Methods
  • MS Methods
  • Automation

Obtain additional analytical detail about your samples

Obtain additional analytical detail about your samples

Get all you need to tackle your liquid chromatography (LC) detection challenges with Waters full portfolio of detectors for UPLC/UHPLC, HPLC, and SFC analysis that are synonymous with sensitivity, stability, and usability.

  • UV Methods
  • MS Methods
  • Automation

Bring the power of mass detection to your lab

Bring the power of mass detection to your lab

Minimize the risk of unexpected coelutions or components and confirm trace components with the analytical confidence of mass detection using the ACQUITY QDa Mass Detector that offers intuitive operation and more information from every sample.

  • UV Methods
  • MS Methods
  • Automation

High performance from a compact design with rapid and reliable quantitative data

High performance from a compact design with rapid and reliable quantitative data

Obtain exceptional analytical flexibility and outstanding sensitivity with the Xevo TQ-S micro that delivers high quality analytical performance injection after injection, even with the most complex sample matrices.

  • UV Methods
  • MS Methods
  • Automation

Ensure your laboratory runs efficiently with Waters advanced software that provides quality and reliable results for increased productivity.

Ensure your laboratory runs efficiently with Waters advanced software that provides quality and reliable results for increased productivity.

Simplify data acquisition, processing, and reporting

Simplify data acquisition, processing, and reporting

Equip your lab with Empower Chromatography Data System (CDS) and gain advanced laboratory data management for your amino acid analyses, including acquisition, processing, and reporting for liquid and gas chromatography instruments.

  • UV Methods
  • MS Methods
  • Automation

Effortlessly transition from laborious manual pipetting procedures to automated processes with Lab Automation solutions from Waters.

Effortlessly transition from laborious manual pipetting procedures to automated processes with Lab Automation solutions from Waters.

Automate the tedious. Focus on the critical

Automate the tedious. Focus on the critical

Obtain simplified and flexible liquid handling with the Waters Andrew+ Pipetting Robot to improve your lab’s efficiency. Andrew+ fully automates the use of connected, manual electronic pipettes and uses innovative labware holders to adapt to your preferred consumables and workflows. By effortlessly adding connected devices and tools for more complex processes such as heating/cooling, shaking, fully automated Solid Phase Extraction (SPE), magnetic bead-based separations and much more, you gain a full walk-away automation solution that easily evolves with your needs while remaining truly intuitive and easy to use. All programmed through the radically simple OneLab software, automating your lab processes has never been more accessible, traceable and compliant.

  • UV Methods
  • MS Methods
  • Automation

Our reliable and robust columns, standards, and sample preparation kits can be easily integrated into your food and feed workflows.

Our reliable and robust columns, standards, and sample preparation kits can be easily integrated into your food and feed workflows.

Accurate amino acid composition analysis starts here

Accurate amino acid composition analysis starts here

Experience accurate and reproducible UPLC, UHPLC, and HPLC amino acid analysis with AccQ•Tag Ultra derivatization kits and columns that are QC tested to ensure repeatable performance.

  • UV Methods
  • MS Methods
  • Automation

Application-specific amino acid standard kits for identification and quantification

Application-specific amino acid standard kits for identification and quantification

Separate, identify, & quantify amino acids in cell culture, protein hydrolysates, foods, and feeds with Waters Amino Acid Analysis HPLC, UHPLC, & UPLC solutions, standards and kits for accurate results.

  • UV Methods
  • MS Methods
  • Automation

Maximize lab efficiency with fewer failed assays and lower instrument downtime

Maximize lab efficiency with fewer failed assays and lower instrument downtime

Reduce failed assays from unknown contaminant peaks and limit instrument downtime in your food testing lab with Waters Standard & Certified HPLC Sample Vials.

  • UV Methods
  • MS Methods
  • Automation

Achieve accurate amino acid results for a large variety of food products using streamlined Waters analytical services.

Achieve accurate amino acid results for a large variety of food products using streamlined Waters analytical services.

Comprehensive analytical services to meet your compliance requirements

Comprehensive analytical services to meet your compliance requirements

Meet your laboratory compliance and data integrity needs while gaining end-to-end support for method development, transfer, and migration with Waters Analytical Services.

  • UV Methods
  • MS Methods
  • Automation

Productivity up. Costs? Way down

Productivity up. Costs? Way down

Safeguard against lost productivity and unexpected downtime with FlexCHOICE mySystem Coverage options designed for your unique lab requirements.​

  • UV Methods
  • MS Methods
  • Automation

Maximize your financial resources

Maximize your financial resources

Take advantage of the most advanced analytical technology available for your laboratory with innovative payment solutions from Waters Capital, and bundle your complete solution in one easy monthly payment.

  • UV Methods
  • MS Methods
  • Automation

The data speaks for itself

The data speaks for itself
Well-separated Cell Culture and Food and Feed aAmino Acid Standards (500 µM) on the ACQUITY Premier Binary Fixed Loop System.
Chromatogram separation of a selection of individual DL-amino acid pairs at 25 ng/mL.
 Typical chromatograms of derivatized undiluted beverage samples.
Amino acid chromatograms of supplement samples in different forms.

Webinars and Resources



  • Application Notebook

Food and Beverage Quality Control and Compositional Testing Application Notebook

Food and Beverage Quality Control and Compositional Testing Application Notebook
  • Application Notebook

Amino Acid Analysis Application Notebook

Amino Acid Analysis Application Notebook
  • Case Study

Liquid Handling Automation System Streamlines Sample Preparation for Nutritional Analysis

Liquid Handling Automation System Streamlines Sample Preparation for Nutritional Analysis
  • White Paper

Improving Method Reproducibility and Efficiency in Food Testing: How Can Liquid Handling Automation Help?

Improving Method Reproducibility and Efficiency in Food Testing: How Can Liquid Handling Automation Help?
  • Webinar

Amino Acid Analysis — Combining Industry Standard Methods with Modern Technology

Amino Acid Analysis — Combining Industry Standard Methods with Modern Technology

Related

The UPLC Amino Acid Analysis Solution is a comprehensive package that combines instrumentation, chemistries, reagents, and performance-qualified methods for turn-key application success.

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Learn more about Amino Acids Testing Solutions.

Learn more about Amino Acids Testing Solutions.

Foods rich in amino acids
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