• Application Note

Analysis of Mouthwash Using XBridge Shield RP18

Analysis of Mouthwash Using XBridge Shield RP18
  • Waters Corporation
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This is an Application Brief and does not contain a detailed Experimental section.

Abstract

This application brief describes the analysis of mouthwash using XBridge Shield RP18 Column.

Introduction

This application brief analyse various compounds including sodium saccharin, domiphen bromide, and cetylpyridinium chloride (Figure 1) using XBridge Shield RP18 Column.

Experimental

Test Conditions

Columns:

XBridge Shield RP18, 4.6 x 100 mm, 3.5 μm

Part Number:

186003044

Mobile Phase A:

0.1 mM CH3COONH4, pH 5.4

Mobile Phase B:

ACN

Flow Rate:

1.2 mL/min

Injection Volume:

20 μL

Sample:

Sodium Saccharin (50 μg/mL), Domiphen Bromide (50 μg/mL), Cetylpyridinium chloride (10 μg/mL) in ACN/CH3COONH4 (5/95)

Column Temp:

30 °C

Sample Temp:

20 °C

Detection:

UV @ 262 nm

Sampling Rate:

5 point/sec

Filter Response:

0.2

Instrument:

Waters Alliance 2695 with 2996 PDA

Gradient:

Results and Discussion

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WA60184, April 2008

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