Lipostar2
Specifically designed for your LC-MS/MS lipidomics research
Lipidomics is a rapidly growing area of omics science allowing researchers to probe changes in the complex lipidome. The detection and identification of lipids of interest poses a significant challenge, mainly associated with data processing, database searching, and lipid identification.
Enhance your understanding of lipids through the Lipostar2, a comprehensive software for LC-MS/MS-based lipidomics (DDA and DIA) that includes many features like raw data import, peak detection, identification, quantification, statistical analysis, trend analysis, support for stable isotope labelling experiments, and biopathways analysis. Leverage Waters LC-MS/MS technologies and Lipostar2 to improve your data processing and visualization and accelerate your lipid analysis.
Lipostar2
Overview
- Meet untargeted and semi-targeted LC-MS-based lipidomics research requirements with a specially developed solution
- Cover all steps in LC-MS-based untargeted and semi-targeted analysis
- Improve annotation accuracy across peak detection, lipid annotation, and lipid pathway analysis
- Obtain high-throughput identification with class-specific fragmentation recognition and identification of oxidised species
Recommended Use: For efficient data processing and visualization in lipidomics research.
Streamline data processing with complete compatibility
Add even greater value to the native capabilities of waters_connect Software Solutions to process and visualize lipidomics data using a streamlined end-to-end workflow that is fully compatible with Waters data including MSE, SONAR, HDMSE, and calculation of CCS values. As a vendor-neutral solution, Lipostar2 lets you utilize software processing capabilities across multiple MS instruments.
Achieve higher confidence in your identifications
Merge positive and negative ion data from the same samples for a higher degree of confidence in your identifications and obtain a clearer picture with 3D peak visualization of HDMSE data using IMS viewer. Easily conduct simple peak and spectra interrogation and peak editing in just a few clicks.
Accelerate your research with an advanced statistical analysis toolbox
Meet all your analysis requirements with a toolbox of unsupervised and supervised multivariate statistical models and T tests while simplifying your ability to identify trends in your data with Trend Analysis for lipids, and quantification tools for plotting your calibration curves.
Leverage fragmentation rules and custom databases
The DB Manager module in Lipostar2 ensures accuracy with lipid class specific fragmentation rules, minimizing false positive rate in the identification step. The software’s intuitive tools simplify complex analyses for seamless insights, leveraging resources like LIPIDMAPS alongside effortless custom database generation from sdf or csv files, including the Waters Lipidomics Profiling CCS library. Lipostar2 assigns scores for mass error, isotopic pattern, fragmentation, and CCS values, enhancing confidence in your results with a traffic light system. Kendrick plots are also available to revise and further reduce false discovery rate.
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