• Application Note

Pseudoephedrine HCL

Pseudoephedrine HCL

  • Waters Corporation
Blister pack of red psuedoephedrine pills

This is an Application Brief and does not contain a detailed Experimental section.

Abstract

This application brief highlights the analysis of Pseudoephedrine HCL using Symmetry columns. 

Introduction

Pseudoephedrine HCL is analysed using Symmetry Guard Columns.

Pseudoephedrine HCL

Experimental

HPLC Method

Column:

Symmetry C8, 3.9 x 150 mm, 5 μm

Guard column:

Symmetry Guard Column, 3.9 x 20 mm, 5 μm

Part numbers:

Column - WAT046970, Guard - WAT054250

Mobile phase:

50 mM potassium phosphate, pH 3.0/methanol 85:15

Flow rate:

1.0 mL/min

Injection volume:

5 μL of 2.88 μg/mL sample

Detection:

UV @ 261 nm

USP Tailing Factors

  1. 1.65 

Results and Discussion

Results

WA31763.136, June 2003