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Fast and Simple Bioanalytical Plasma Sample Extraction Using Oasis HLB SPE for High Analyte Recovery

Fast and Simple Bioanalytical Plasma Sample Extraction Using Oasis HLB SPE for High Analyte Recovery

  • Kim Van Tran
  • Mary Trudeau
  • Waters Corporation

본 응용 개요서는 구체적인 실험 내용을 포함하지 않습니다.

본 응용 개요서는 구체적인 실험 내용을 포함하지 않습니다.

Abstract

This application note describes the fast and simple bioanalytical plasma sample extraction using Oasis HLB solid phase extraction, requiring no protocol method development, for high extraction recovery of several small molecule pharmaceuticals.

Experimental

Sample Preparation & Extraction.

LC-MS Analysis

UPLC Gradient Table

Results and Discussion

High Analyte Recovery from Plasma using Oasis HLB SPE

Figure 1. Demonstration of Oasis HLB SPE Performance requiring no protocol optimization, with >78% recovery and matrix effects <20% from plasma.

Ordering Information

720008168, December 2023

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