Fast and Simple Bioanalytical Plasma Sample Extraction Using Oasis HLB SPE for High Analyte Recovery
Fast and Simple Bioanalytical Plasma Sample Extraction Using Oasis HLB SPE for High Analyte Recovery
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Abstract
This application note describes the fast and simple bioanalytical plasma sample extraction using Oasis HLB solid phase extraction, requiring no protocol method development, for high extraction recovery of several small molecule pharmaceuticals.
Experimental
Sample Preparation & Extraction.
LC-MS Analysis
UPLC Gradient Table
Results and Discussion
High Analyte Recovery from Plasma using Oasis HLB SPE
Figure 1. Demonstration of Oasis HLB SPE Performance requiring no protocol optimization, with >78% recovery and matrix effects <20% from plasma.Ordering Information
720008168, December 2023