Vitamin Testing Solutions

Vitamin Testing Solutions

Implement cost-effective methods for vitamin testing across a range of food and beverage products with Waters standardized and reliable workflows. Waters solutions provide separation and detection capabilities to accelerate time to results, protect consumers and brands, and ensure the accuracy of product label claims.

Implement cost-effective methods for vitamin testing across a range of food and beverage products with Waters standardized and reliable workflows. Waters solutions provide separation and detection capabilities to accelerate time to results, protect consumers and brands, and ensure the accuracy of product label claims.

Vitamin c effervescent tablet is dissolving in glass of water
Vitamin c effervescent tablet is dissolving in glass of water

Overview

Ensuring that the vitamin content of products is consistent with the label claim isn’t just good practice – it’s a regulatory requirement. Waters recognizes the crucial role that rapid, reliable, and cost-effective analytical methods play in accurately monitoring nutritional content and ensuring compliance with product labels.

Waters vitamin solutions enable food and beverage testing laboratories to create efficient testing methods, supporting manufacturers in:

  • Standardizing analysis for a range of complex water- and fat-soluble vitamins
  • Testing for multiple vitamins across a range of food and beverage products
  • Minimizing overages of vitamins and other raw products
  • Reducing the number of methodologies required
  • Rapidly confirming nutritional value for vitamin specifications and label compliance

Rows of bottled juices or sports drinks

Applications

Fat-soluble vitamin analysis is complicated by matrix complexity and the thermal instability of compounds, as well as a lack of standardized methods for differentiating natural from synthetic vitamins. Waters innovative solutions, including the ACQUITY UPC2 System and multi-dimensional liquid chromatography, overcome these challenges by enhancing solubility and stability, improving efficiency, and offering cost-effectiveness in routine quality control environments.

Fat-soluble vitamin analysis is complicated by matrix complexity and the thermal instability of compounds, as well as a lack of standardized methods for differentiating natural from synthetic vitamins. Waters innovative solutions, including the ACQUITY UPC2 System and multi-dimensional liquid chromatography, overcome these challenges by enhancing solubility and stability, improving efficiency, and offering cost-effectiveness in routine quality control environments.


Vitamin K in wooden spoon with bottle of tablets and green herbs


Blog: Recent Trends in Beverage Testing – Vitamins

Today’s food and beverage manufacturers must continually innovate to meet increasing consumer demand for products that support lifestyle and health goals. Read our blog to understand how Waters HPLC and UPLC solutions enable reliable, accurate, and efficient testing methods to ensure that finished beverage products meet manufacturers’ specifications and nutritional label claims.

Today’s food and beverage manufacturers must continually innovate to meet increasing consumer demand for products that support lifestyle and health goals. Read our blog to understand how Waters HPLC and UPLC solutions enable reliable, accurate, and efficient testing methods to ensure that finished beverage products meet manufacturers’ specifications and nutritional label claims.


Sports drinks in ice tub

Solutions


With Waters systems, streamline analysis, and accelerate sample throughput tailored to your vitamin testing labs.

With Waters systems, streamline analysis, and accelerate sample throughput tailored to your vitamin testing labs.

See clearly and consistently, with confidence

See clearly and consistently, with confidence

Reduce non-specific adsorption from metal interactions in HPLC and UHPLC applications and obtain higher quality, reproducible data with the Arc Premier System.

  • Fat-Soluble Vitamin Testing
  • Water-Soluble Vitamin Testing

The next evolution in separation science is here

The next evolution in separation science is here

Minimize metal-sensitive analyte loss and improve recovery with the ACQUITY Premier System for ultra-performance liquid chromatography analysis.

  • Fat-Soluble Vitamin Testing
  • Water-Soluble Vitamin Testing

Performance that advances your lab

Performance that advances your lab

Get the flexibility of quaternary or binary solvent blending and decrease your time to result with the ACQUITY UPLC H-Class PLUS System to improve the characterization of your most complex samples.

  • Fat-Soluble Vitamin Testing
  • Water-Soluble Vitamin Testing

The ease of reversed-phase meets the power of normal-phase

The ease of reversed-phase meets the power of normal-phase

Address routine and complex separation challenges while delivering reliability, robustness, sensitivity, and increased throughput of convergence chromatography techniques with the ACQUITY UPC2 System.

  • Fat-Soluble Vitamin Testing

Highly reliable, low complexity, accurate routine analysis

Highly reliable, low complexity, accurate routine analysis

Replicate and improve the performance of your existing LC vitamin analysis methods without compromising data quality with Arc HPLC System.

  • Fat-Soluble Vitamin Testing
  • Water-Soluble Vitamin Testing

A new era of intuitive simplicity

A new era of intuitive simplicity

Reduce human errors, HPLC system downtime, and generate consistent global method performance with the Alliance iS HPLC System to multiply the productivity and efficiency of your QC lab.

  • Fat-Soluble Vitamin Testing
  • Water-Soluble Vitamin Testing

Separate beyond question with the power of mass detection

Separate beyond question with the power of mass detection

Minimize the risk of unexpected coelutions or components and confirm trace-components with certainty with the ACQUITY QDa II Mass Detector and enhance the analytical value of each analysis.

  • Fat-Soluble Vitamin Testing
  • Water-Soluble Vitamin Testing


The data speaks for itself

The data speaks for itself
Significant improvements in peak shape and sensitivity of vitamin B chromatograms are observed using the ACQUITY Premier LC system Significant improvements in peak shape and sensitivity of vitamin B chromatograms are observed using the ACQUITY Premier LC system and column with MaxPeak HPS Technology (green traces) compared to the stainless steel setup (red traces). (A) demonstrates these enhancements from the initial injections, while (B) shows the sustained benefits after extensive system use.
Mass detection enables the detection of vitamins at low levels Mass detection enables the detection of vitamins at low levels, as demonstrated by the SIR chromatogram of vitamin B12 using the ACQUITY QDa Mass Detector (A), compared to the UV chromatogram (B).
The stereoisomers of all-rac-α-tocopheryl acetate were separated into two main peaks The stereoisomers of all-rac-α-tocopheryl acetate were separated into two main peaks, while RRR-α-tocopheryl acetate showed a single sharp peak within 15 minutes on an ACQUITY UPC² System, offering a reliable method to differentiate between natural and synthetic vitamin E.
Chromatogram for the standard of vitamin A, four isoforms of vitamin E, and two vitamin D, acquired on ACQUITY Arc 2D-LC System Chromatogram for the standard of vitamin A, four isoforms of vitamin E, and two vitamin D, acquired on ACQUITY Arc 2D-LC System.

Webinars and Resources


Webinar: Rapid Analysis of Vitamins in Fortified Food and Beverages

Webinar: Rapid Analysis of Vitamins in Fortified Food and Beverages

  • Application Notebook

Food and Beverage Quality Control and Compositional Testing

Food and Beverage Quality Control and Compositional Testing
  • Case Study

Manufacturer Reduces Vitamin QC Analysis Times by Up to 90%

Manufacturer Reduces Vitamin QC Analysis Times by Up to 90%
  • Case Study

Improving Standards for Vitamin Analysis using Mass Detection

Improving Standards for Vitamin Analysis using Mass Detection
  • Case Study

Liquid Handling Automation System Streamlines Sample Preparation for Nutritional Analysis

Liquid Handling Automation System Streamlines Sample Preparation for Nutritional Analysis
  • Webinar

Technologies for Reliable Water and Fat-Soluble Vitamins Analysis

Technologies for Reliable Water and Fat-Soluble Vitamins Analysis

Related

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Support food and beverage analysis workflows to maintain product consistency and quality with Waters sugar substitute testing solutions.

Ensure product nutrition labeling compliance and adhere to food manufacturing specifications with Waters amino acid analysis solutions for accurate, simplified testing of food, beverage and feed samples.

Confirm products meet specifications and nutritional label claims with Waters manual and automated solutions for amino acid testing, enabling laboratories.

Learn more about Vitamin Testing Solutions.

Learn more about Vitamin Testing Solutions.

Vitamin c effervescent tablet is dissolving in glass of water