• Application Note

Captopril

Captopril

  • Waters Corporation

This is an Application Brief and does not contain a detailed Experimental section.

Abstract

This application brief demonstrates analysis of captopril.

Introduction

The compound analyzed in this study is captopril.

Compounds

USP Tailing Factors

Captopril

1.0

Captopril Disulfide

1.2

Experimental

HPLC Method

Column:

Symmetry C18, 3.9 x 150 mm, 5 μm

Part number:

WAT046980

Mobile phase:

0.1% phosphoric acid in water/methanol 60:40

Flow rate:

1.0 mL/min

Injection volume:

10 μL of 200 μg/mL captopril and 20 μg/mL of captopril disulfide

Temperature:

40 °C

Detection:

UV @ 220 nm

Results and Discussion

Featured Products

WA31763.46, June 2003

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