• Application Note

Methylphenidate HCL

Methylphenidate HCL

  • Waters Corporation
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This is an Application Brief and does not contain a detailed Experimental section.

Abstract

This application brief demonstrates the analysis of Methylphenidate HCL using Symmetry Columns.

Introduction

The compound analyzed in this study is Methylphenidate HCL. 

Methylphenidate HCL

Experimental

HPLC Method

Column:

Symmetry C8, 3.9 x 150 mm, 5 µm

Guard Column:

Symmetry Guard Column 3.9 x 20 mm, 5 µm

Part numbers:

Column - WAT046970, Guard - WAT054250

Mobile phase:

20 mM potassium phosphate, pH 2.18/methanol 80:20

Flow rate:

1.0 mL/min

Injection volume:

15 µL of 200 µg/mL

Detection:

UV @ 254 nm

USP Tailing Factors

  1. 1.5 

Results and Discussion

Results

WA31763.100, June 2003

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