PoraPak Rxn

PoraPak Rxn

Fast, simple, and cost effective synthesis cleanup

Fast, simple, and cost effective synthesis cleanup

Waters offers PoraPak Rxn, a family of polymer-based chromatography products for superior cleanup of synthetic reactions. PoraPak Rxn products are available in two chemistries: PoraPak Rxn CX, a strong cation-exchange sorbent and PoraPak Rxn RP, a reversed-phase sorbent.

PoraPak Rxn sorbents are based on copolymers that exhibit the following properties:

  • Hard material that does not develop increasing back pressure with flow
  • Little swelling or shrinking across a range of solvents and pH extremes
  • Low hydraulic resistance enables flow by gravity
  • pH extreme tolerance without dissolution or hydrolysis, both limitations of silica-based sorbents
PoraPak Rxn, a family of polymer-based chromatography products for superior cleanup of synthetic reactions. PoraPak Rxn

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PoraPak Rxn chromatography cartridge designed to enhance the efficiency and speed of synthetic reaction cleanups in laboratories. It combines cation-exchange and reversed-phase chromatography functionalities, allowing it to separate compounds based on ionic charge and polarity. The cation-exchange feature effectively removes positively charged ions, while the reversed-phase function targets non-polar compounds, making it versatile for various separation tasks.

Constructed from durable polymer-based materials, PoraPak Rxn cartridges are robust and chemically resistant, suitable for use with a wide range of solvents and harsh conditions typically encountered in synthetic chemistry. This ensures consistent performance and longevity, reducing the need for frequent replacements.

These cartridges are particularly useful for fractionation, dividing complex mixtures into individual components to isolate desired products from by-products and impurities. They are also instrumental in the de-watering process, removing water from reaction mixtures to prevent interference in subsequent steps or analytical techniques.

The advantages of PoraPak Rxn cartridges include increased speed and efficiency compared to traditional cleanup methods. Their design allows for quicker processing times, which is beneficial in high-throughput environments. The dual-functionality enhances separation effectiveness, leading to higher purity and improved yields of isolated compounds. The use of pre-packed cartridges simplifies the cleanup process, minimizing errors and variability.

PoraPak Rxn cartridges can be used in both automated and manual setups, making them adaptable to various laboratory environments. They are compatible with a wide range of chromatography equipment, ensuring seamless integration into existing workflows. Overall, PoraPak Rxn cartridges offer a reliable, efficient, and convenient solution for reaction cleanups, significantly improving the productivity and quality of synthetic processes.