Sirocco Protein Precipitation Plate

Sirocco Protein Precipitation Plate

Clear, high-throughput in-well protein precipitation starts here

Clear, high-throughput in-well protein precipitation starts here

Saving time and improving efficiency in your lab is critical. One way to do that is to streamline your sample handling process by eliminating the time-consuming sample handling steps of traditional protein precipitation (PPT).

The Sirocco Plate is the most technologically advanced 96-well protein precipitation plate on the market. With its unique membrane and valve-tip technology, you can carry out high-throughput in-well protein precipitation of biological samples without fear of cloudy filtrates or clogged devices. You can also speed processing time with Sirocco’s optimum performance, which enables you to simplify in-well sample processing and complete recovery of clean filtrates from smaller plasma sample volumes.

Sirocco Protein Precipitation Plate Sirocco Protein Precipitation Plate
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Specifications

Overview

  • Maximize sample recovery with a state-of-the-art design
  • Eliminate time-consuming sample handling steps for increased throughput
  • Increase confidence in results by minimizing sample crosstalk
  • Control flow until vacuum is applied with unique valve design
  • Maximize system uptime with precipitate-free filtrate instead of traditional protein precipitation methods
  • Suitable for manual or automated sample processing

Recommended Use: To increase laboratory throughput and conduct protein precipitation in significantly less time.

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Sirocco PPT vs. Classical PPT

Save time and increase your laboratory throughput with Sirocco 96-well Protein Precipitation Plate. With Sirocco, you can process samples in significantly less time than with traditional PPT. 

Achieve excellent recoveries across all analytes

The Sirocco PPT plate is highly reproducible and linear, with analytes examined having >95% recovery. This 96-well protein precipitation plate was validated for performance using a variety of polar and non-polar acids, bases, and neutral compounds spiked into porcine and rat plasmas looking for high recoveries.

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The Sirocco Protein Precipitation Plate is a specialized tool designed to make the process of protein precipitation in labs faster and easier. Protein precipitation is an important step in preparing biological samples for tests like liquid chromatography-mass spectrometry (LC-MS). This method helps to remove proteins that can interfere with the analysis. Traditional methods, such as centrifugation and filtration, can be time-consuming, but the Sirocco plate streamlines the process, making it much more efficient and convenient for labs.

One of the key advantages of the Sirocco plate is its 96-well format, allowing labs to process multiple samples at once. This high-throughput capacity is especially beneficial for labs dealing with large volumes of samples, as it significantly reduces preparation time and boosts overall productivity. The plate works by allowing the user to directly add organic solvents, like acetonitrile or methanol, to cause proteins to precipitate. The precipitated proteins are then easily removed through filtration, leaving a clean sample ready for analysis without the need for lengthy centrifugation steps.

The design of the Sirocco plate also ensures that sample loss is minimized while maintaining maximum recovery of analytes. This is particularly important when dealing with small sample volumes, where precision is critical. By standardizing the protein precipitation process, the plate helps improve the consistency of results, which is crucial in fields such as pharmacokinetics, drug metabolism, and toxicology. Additionally, its compatibility with automated liquid handling systems means that it can be easily integrated into automated workflows, allowing labs to process even more samples with greater speed and accuracy.

Not only does the Sirocco plate save time and increase throughput, but it is also user-friendly. The streamlined design reduces the number of steps needed compared to traditional methods, making the overall workflow more efficient. Whether in small labs or large bioanalytical facilities, the plate helps ensure more reliable and consistent results, allowing researchers to handle large sample sets with confidence and ease.

To conclude, the Sirocco Protein Precipitation Plate offers a practical solution for labs looking to optimize their sample preparation processes. By improving speed, efficiency, and reliability, this tool helps labs reduce time spent on preparation, increase their capacity for handling samples, and enhance the quality of their analytical results.