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FlexMETHODS Method Migration Service for Validated LC Methods

FlexMETHODS Method Migration Service for Validated LC Methods

Reduce the burden of updating your aging HPLC systems

Reduce the burden of updating your aging HPLC systems

Concerned about moving your validated test methods to a new high-performance liquid chromatography (HPLC) system? Worried about reproducing results or wondering how you will find the time to implement a new HPLC system?

FlexMETHODS Method Migration Service is delivered by Waters analytical professional services experts and designed to remove the burden associated with upgrading to new HPLC technology. With FlexMETHODS, Waters will support the safe migration of your trusted methods, alleviating your concerns and helping to keep your laboratory up to date.

Trust Waters experts with your methods. FlexMETHODS Method Migration Service for Validated LC Methods

Overview

  • Trust Waters separations experts to professionally and safely guide you through a risk-based approach to translating methods to modern platforms
  • Reduce the time you spend troubleshooting method performance when migrating methods with our tried and tested professional services training and enablement package
  • Learn to implement a risk-based approach to method migration, enabling you to conduct future migrations successfully
  • Access virtual and on-site support from Waters analytical professional services team 
  • Minimize disruption to ongoing projects and the impact on your laboratory operating costs

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Take a risk-based approach to method migration

The risk-based approach to instrument assessment helps to ensure that your new HPLC assets and configuration are fit for their intended purpose, significantly improving your likelihood of meeting System Suitability Tests (SST) the first time around.

The Waters Professional Services team will help you to:

  • Understand key considerations when replacing your assets
  • Focus on the relevant performance and technical aspects of the instrument specifications
  • Predict the impact of a new instrument on the analytical procedure performance
  • Proactively prevent issues through application of appropriate control strategies

Read how Eurofins BPT Toronto adopted a risk-based approach to successfully migrate their test methods to the Arc HPLC, while ensuring data equivalency and regulatory compliance.

Start seeing the benefits of modern technology

There are significant advantages to replacing aging HPLCs, not least the reduction of unscheduled, unexpected downtime, which can have a direct impact on an organization’s productivity and project completion timelines.

In addition, modern HPLC platforms like Waters Arc HPLC can improve repeatability and consistency of results, while offering lower analyte carryover, higher injection precision, and higher back-pressure tolerance.

Read our case study with Medinsa, a Spanish contract organization that realized a threefold reduction in the number of test-related incidents following the upgrade of their aging HPLCs to the Waters Arc HPLC System. 

FlexMETHODS is available to Waters customers on Empower when replacing aging (Waters or other vendor) systems with new, equivalent, Waters HPLC instruments.

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Payment Solutions
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The FlexMETHODS Method Migration Service is a specialized solution to help laboratories transition validated liquid chromatography (LC) methods to modern LC systems efficiently and without compromising quality or compliance. This service ensures your methods maintain accuracy, reproducibility, and regulatory adherence while optimizing them for the capabilities of next-generation LC platforms.

The process starts with a comprehensive assessment of your current validated methods. Experts analyze critical parameters, identify potential challenges, and create a customized migration plan tailored to your lab"s specific needs. This ensures a seamless transition, addressing factors like system compatibility and key performance requirements.

Once the migration plan is in place, the service includes rigorous testing and optimization to ensure methods perform reliably on the new system. Adjustments to parameters such as flow rates, gradients, and injection volumes are made to maximize efficiency and performance. Validation support is provided to confirm that the migrated methods meet industry standards for accuracy, precision, and robustness. Detailed documentation is also supplied to ensure regulatory compliance and simplify submissions.

A key advantage of the service is its focus on minimizing downtime. The migration process is designed to disrupt workflows as little as possible, allowing your lab to quickly adapt to the new system and benefit from enhanced capabilities, such as improved sensitivity, faster analysis times, and higher resolution. The process also promotes cost efficiency by optimizing methods for reduced solvent usage and operational costs.

Throughout the migration, you"ll have access to a team of chromatography experts who offer guidance and troubleshooting support. Their expertise ensures that your methods are adapted effectively, helping you unlock the full potential of modern LC technology.