Columns for Antibody Drug Conjugates (ADC)

SKU: 176000863
ACQUITY UPLC BEH C18 Column, 130Å, 1.7 µm, 2.1 mm X 50 mm, 3/pk

ACQUITY UPLC BEH C18 Column 130Å 1.7 µm | 2.1 mm X 50 mm | 3/pk | 176000863


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Product Description

As the premier column for method development, the 1.7 um ACQUITY UPLC BEH C18 sorbent provides you with the most universal column choice for UPLC separations. The

trifunctionally bonded BEH particle gives you the widest usable pH range (pH 1-12), superior low pH stability, and ultra-low column bleed for high sensitivity MS applications.

Specifications

  • Chemistry

    C18

  • Separation Mode

    Reversed Phase

  • Particle Substrate

    Hybrid

  • pH Range Min

    1 pH

  • pH Range Max

    12 pH

  • Maximum Pressure

    18000 psi (1240 Bar)

  • Endcapped

    Yes

  • Silanol Activity

    Low

  • Particle Shape

    Spherical

  • Particle Size

    1.7 µm

  • Endfitting Type

    Parker-style

  • Pore Size

    130 Å

  • Format

    Column

  • Surface Area

    185

  • System

    UHPLC, UPLC

  • Particle Technology

    BEH

  • USP Classification

    L1

  • Inner Diameter

    2.1 mm

  • Length

    50 mm

  • Carbon Load

    18 %

  • eCord

    Yes

  • UNSPSC

    41115709

  • Brand

    ACQUITY UPLC

  • Product Type

    Columns

  • Units per Package

    3 pk

Product Support

Documents

Documents



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ACQUITY UPLC BEH C18 Column, 130A, 1.7 µm, 2.1 mm X 50 mm, 3/pk

Designed, tested, and guaranteed for use in applications up to 15000 psi (1000 bar), ACQUITY UPLC columns are the right lab equipment you need with unprecedented efficiency, ruggedness, and throughput. As a part of the ACQUITY UPLC system, these columns are manufactured in a cGMP, ISO 9001 certified plant that uses ultra-pure reagents. All ACQUITY UPLC BEH columns are chromatographically tested with neutral, acidic, and basic analytes and the results are helpful to extremely narrow specification ranges, promising excellent and reproducible performance in your laboratory.

With unrivaled levels of peak asymmetry, efficiency, and chemical stability, the 1.7 µm columns are versatile and offer high-performance separation on a wide range of analytes. Able to operate between 1 and 12 pH, the columns are trifunctionally-bonded alkyl columns, The power of pH can be harnessed to impact retention, selectivity, and sensitivity of ionizable compounds. These benefits are all delivered along with superior high and low pH stability by combining the low pH and high pH stability of the 1.7 µm BEH particle.

The BEH technology incorporates a proprietary end-capping process, producing optimal peak shape for bases. This innovation along with bonding chemistries and particle synthesis help to create the sharpest peaks, highest efficiencies, and maximum MS sensitivities. This is all done without needing to switch between UPLC mode and the conventional HPLC mode, as the same unit is capable of both without modification.

ACQUITY UPLC BEH C18 VanGuard Pre-column, 130Å, 1.7 µm, 2.1 mm X 5 mm, 3/pk are a part of the ACQUITY UPLC system, built to allow chromatographers to fully harness the power of sub-2 µm particle columns. In order to realize this ability, the UPLC system doesn't compromise sample throughput to maintain fidelity. With ultra-speed, ultra-resolution, and ultra-sensitivity, you will be more accurate and efficient using these rugged and stable columns.

What is ultra-speed?

The speed of separation in chromatography can impact the efficiency or peak shape, therefore more speed is desirable. When the column length and particle size are reduced by the same ratio, both the resolving power of the column and the resolution or peak capacity can remain intact, while the separation is achieved in less time. UPLC is able to achieve this result using low system volume, fast detector, short cycle time sample managers with low carryover, small and rugged particles, and Waters advanced column hardware and packing techniques.

What is UPLC?

UPLC, short for Ultra Performance Liquid Chromatography, represents a revolutionary advancement in the realm of separation science that surpasses the capabilities of HPLC (High Performance Liquid Chromatography). By utilizing compact UPLC columns densely packed with minute particles measuring between 1.7 and 1.8 µm, laboratories gain access to an unparalleled level of chromatographic performance. UPLC technology empowers labs to elevate resolution, sensitivity, and speed to new heights, all while maintaining the utmost integrity and precision.