BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 2.1 mm X 50 mm, 1/pk w/ Intact mAb and mAb Subunit Standards

To overcome analytical challenges inherent in the reverse-phase analysis of IgG monoclonal antibodies and their fragments, you need an analytical column that’s more than capable of overcoming those challenges. And with the BioResolve RP mAb Polyphenyl Column, you get that and so much more. This breakthrough separation tool offers improved peak capacity for better component resolution, which is perfect for scientists who are working in method development. Plus, if you need to verify system performance before performing separations, we’ve included one vial each of the Intact mAb Mass Check Standard and mAb Subunit Standard with this column. Improve upon your current mAb analysis workflow with the help of the BioResolve RP mAb Polyphenyl Column today.

The BioResolve RP mAb Polyphenyl Column may offer rugged silica particles within it, but over time this column could become contaminated if you don’t care for it properly. Proper sample purification protocols should always be followed, as well as proper column cleaning procedures. But what about the contaminants that may be lingering in the mobile phase stream?
To remove those from your workflow, we’re happy to provide the BioResolve RP mAb Polyphenyl VanGuard Cartridge. This guard cartridge sits between your mobile phase injector and analytical column to act as an extra step of protection. As the mobile phase stream goes through the cartridge, the cartridge picks up any contaminants it may find and removes them before they negatively impact your separations.

The BioResolve RP mAb Polyphenyl Column is specifically designed for the LC or LC-MS analysis of IgG monoclonal antibodies and their fragments. But how this column achieves such a daunting task is even more interesting. In every BioResolve RP mAb Polyphenyl Column lies a group of rugged silica particles that have been functionalized by a polyphenyl bonding process that was specifically designed for the LC or LC-MS analysis of monoclonal antibodies. And with minimal injection-to-injection carryover exhibited by this column, your confidence in your analyses will only increase.

Before checking out with the BioResolve RP mAb Polyphenyl Column, make sure to grab all the lab essentials you need at Waters. We offer quality control reference materials, classic chromatography consumables, full LC-MS systems and various resources to help improve your workflows. Shop lab equipment to explore everything we have to offer.