BioResolve RP mAb Columns contain 2.7-μm superficially-porous-silica particles having an average pore diameter of 450Å. The particles are functionalized with a proprietary polyphenyl bonding process that was specifically designed for LC or LC-MS analyses of intact IgG monoclonal antibodies and their fragments. This P/N also includes one vial of the Intact mAb Mass Check Standard (P/N 186006552) and one vial of the mAb Subunit Standard (P/N 186008927).
Separation Mode |
Reversed Phase |
Particle Size |
2.7 µm |
Pore Size |
450 Å |
UNSPSC |
41115709 |
Brand |
BioResolve |
Product Type |
Columns |
Units per Package |
1 pk |
BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 2.1 mm X 100 mm, 1/pk w/ Intact mAb and mAb Subunit Standards
The BioResolve RP mAb Columns comprise 2.7-μm superficially porous silicon dioxide particles with an average pore diameter of 450-Å. A unique poly-phenyl bonding technique that was created especially for LC or LC-MS analysis of intact IgG monoclonal antibodies and their fragments is used to functionalize the particles. Additionally, this P/N contains one vial each of the mAb Subunit Standard (P/N 186008927) and the Intact mAb Mass Check Standard (P/N 186006552). The BioResolve RP mAb Polyphenyl Column from Waters is a brand-new method for examining whole proteins in mAbs and ADCs. Column-to-column chemistry of the BioResolve RP mAb Polyphenyl Column can be used on UPLC, UHPLC, and HPLC platforms.
Add the BioResolve RP mAb Polyphenyl Column to your lab to take advantage of its special features that make it a perfect piece of lab equipment. The analytical column can improve component resolution and peak capacity. The laboratory apparatus also features little injection-to-injection carryover for increased analytical assurance. With the BioResolve RP mAb Polyphenyl Column, you can work at lower temperatures with minimal on-column sample degradation and yet achieve high performance regardless of the LC apparatus used.
The packing material for the BioResolve RP mAb Polyphenyl Column is produced in a cGMP, ISO 9001-certified facility using incredibly pure reagents. Each batch of BioResolve RP mAb Polyphenyl material is qualified using the Waters mAb Subunit Standard (p/n: 186008927), and the results are held to certain specification ranges to ensure reproducible performance. Additionally, the effectiveness of each column is assessed, and an eCord with a Performance Test Chromatogram and Certificate of Analysis is attached. The same information is also accessible to users of non-Waters LC systems who do not have an eCord reader.
Browse through our catalog, or check out our website to review the full list of products available from Waters. You can shop for lab equipment as per your laboratory requirements from our website directly.
You may also be interested in MassPREP Protein Standard Mix; Ribonuclease A, Cytochrome c, bovine serum albumin, myoglobin, enolase, and phosphorylase b are all components of the MassPREP Protein Standard Mix. Different proteins with different isoelectric points, molecular weights, and hydrophobicities are present in this mixture. These features offer the user a desirable intact protein mixture that may be put to use in a variety of ways. Similar to the QCRM product line, it is advised that this standard be utilized frequently for testing column and system performance.
Why Can Only Cations Be Found in Mass Spectrometry?
Mass spectrometry is a powerful technique used to determine the mass of charged particles. When analyzing samples using mass spectrometry, only ions are detected and identified, while neutral molecules do not generate a signal. This selective identification of ions enables precise analysis and characterization of the charged species present in the sample.