BioResolve SCX mAb Column, 3 µm, 4.6 mm x 100 mm 1/pk, with mAb Charge Variant Standard

A wide variety of monoclonal antibodies are frequently separated properly and consistently with charge variant quantification using strong cation-exchange analysis. However, a chromatography column that can easily tolerate chromatographic conditions is required for SCX analysis to be successful. Simply, the BioResolve SCX mAb Column provides the flexibility and stiffness you need to get beyond those obstacles. And because this column offers charge variation analysis of mAbs and other proteins, we provide LC-MS users with a platform that uses strong salt and pH gradient techniques to boost your analyses. This P/N also contains one vial of the mAb Charge Variant Standard (P/N 186009065).

The non-porous polymeric particles inside the BioResolve SCX mAb Column actively strive to reduce analyte band spread to increase mAb separations, which also gives you superior component recovery, peak shape, and component resolution. And because we care so much about how you use this column for method development, we have set it up to have a low injection-to-injection carryover rate during method transfer. In addition to this, this column is LC system independent, allowing for unrestricted use on all UHPLC, HPLC, and UPLC systems. You can repeatedly obtain strong and high-resolution mAb separations in this method.

Waters provides much more than only BioResolve SCX mAb Columns to help you comprehend the manufacture of biotherapeutic drugs. Also available are solution packages to improve your workflow, lab informatics, and data management software, quality control reference materials, and everything else you need to run a successful lab. Shop for lab equipment to furnish your lab with all you need.

Your analytical workflow should constantly take precautions to keep your BioResolve SCX mAb Column clean. In addition to following the right sample purification procedures, we advise including a BioResolve SCX mAb VanGuard Cartridge in your workflow. Before pollutants clog your analytical column and reach it, this guard cartridge actively eliminates them from the mobile phase stream. Additionally, this cartridge can be cleaned in the same manner as your analytical column and is reusable several times.