XTerra RP18 columns are general purpose, hybrid-based, reversed-phase C18 columns that incorporate Waters innovative embedded polar group technology to improve peak shape performance for highly basic compounds. These first generation columns provide superior pH stability compared to a silica-based column.
Chemistry |
C18 |
Separation Mode |
Reversed Phase |
Particle Substrate |
Hybrid |
pH Range Min |
2 pH |
pH Range Max |
12 pH |
Maximum Pressure |
6000 psi (415 Bar) |
Endcapped |
Yes |
Bonding Technology |
Shield RP18 |
Silanol Activity |
Low |
Particle Shape |
Spherical |
Particle Size |
5 µm |
Endfitting Type |
Waters |
Pore Size |
125 Å |
Format |
Column |
Surface Area |
175 |
System |
HPLC |
USP Classification |
L1 |
Inner Diameter |
4.6 mm |
Length |
250 mm |
Carbon Load |
15 % |
UNSPSC |
41115709 |
Brand |
XTerra |
Product Type |
Columns |
Units per Package |
1 pk |
FAQs about Xterra Shield RP18 Column
What is the recommended flow rate for the Waters Xterra Shield RP18 column?
The recommended flow rate for the Waters Xterra Shield RP18 column is 0.5-1.0 mL/min.
What is the particle size of the Xterra Shield RP18 column?
The Xterra Shield RP18 column has a particle size of 5 μm.
Can the Xterra Shield RP18 column be used for both analytical and preparative applications?
Yes, the Xterra Shield RP18 column is suitable for both analytical and preparative applications.
What is the column dimensions of the Xterra Shield RP18 column?
The Xterra Shield RP18 column has dimensions of 4.6 mm x 250 mm.
How many injections can be performed with a single pack of the Xterra Shield RP18 column?
A single pack of the Xterra Shield RP18 column allows for approximately 200 injections.
What is the pH range of the XTerra Brand of columns?
The XTerra brand has two variations, the MS columns and the RP columns. However, both the variations offer distinct advantages over their silica counterparts in terms of the wide-scale pH range. The MS columns offer stable chemical analysis between pH range (1-12) while the RP columns’ pH range is 2-12. Even though the columns are designed to have greater lifespans, they are still finite and buffers will be a determining factor in the lifetimes. The nature of the buffers as well as thor concentration and temperature will all impact the lifetime of the columns. High pH use of Phosphate is not recommended, even though it will generally still provide a better lifespan than silica-based columns.
Why are HPLC columns silica-based?
As the main component of HPLC, the column is responsible for the separation of sample components. Because of silica's particle size and porosity, it aids in separation and is inert, not reacting with mobile phases. This makes it ideal for HPLC as it can be used to analyze the compounds of varying chemical natures. In HPLC, the silica would be known as the stationary phase.