SKU: 186004032
MassPREP Micro Desalting Column

MassPREP Micro Desalting Column | 186004032

Streamline Purchasing with Customized Quotes

Streamline Purchasing with Customized Quotes

Shop on Waters.com and add items to your cart

Navigate to the Shopping Cart

Select Request a Quote to get your quote instantly

Learn More

Product Description

The MassPREP on-line desalting column can effectively desalt proteins prior to LC-MS analyses. Because non-volatile salts (e.g., NaCl) cansuppress ionization of intact proteins leading to poor detection sensitivity, it is important to remove or significantly minimize the introduction ofthese compounds into the mass analyzer. The reversed-phase phenyl material contained in MassPREP on-line column successfully “traps” proteins,allowing the salts to be washed to waste prior to protein elution into the mass spectrometer. With an optimized LC-MS method, cycle times as lowas 4 minutes (for intact antibody) and 10 minutes (for reduced antibody) are achievable.

Specifications

  • Chemistry

    Phenyl

  • Separation Mode

    Reversed Phase

  • Particle Substrate

    Polymethacrylate

  • pH Range Min

    2 pH

  • pH Range Max

    12 pH

  • Endcapped

    Yes

  • Bonding Technology

    Phenyl-Hexyl

  • Molecular Weight Range Min

    1000

  • Molecular Weight Range Max

    1000000

  • Particle Shape

    Spherical

  • Particle Size

    20 µm

  • Endfitting Type

    Direct-Connect

  • Pore Size

    1000 Å

  • Format

    Direct Connect Column

  • USP Classification

    L11

  • Inner Diameter

    2.1 mm

  • Length

    5 mm

  • Carbon Load

    15 %

  • UNSPSC

    41115709

  • Application

    Protein

  • Brand

    MassPREP

  • Product Type

    Columns

  • Units per Package

    1 pk

Product Support

Documents

Documents

What do you want to do?

What do you want to do?
Need Help?
Back To Top Back To Top

MassPREP Micro Desalting Column

Enhance your liquid chromatography-mass spectrometry (LC-MS) applications with the remarkable MassPREP Micro Desalting Column, a high-performance on-line desalting solution. With 3 µm particles boasting a 100Å pore size, a length of 5 mm, and an inner diameter of 2.1 mm, this column is engineered for optimal performance. Packed with a hydrophobic phenyl stationary phase, it effectively separates a wide array of organic compounds with precision. The MassPREP Micro Desalting Column is an invaluable asset in diverse LC-MS applications, revolutionizing the analysis of peptides, proteins, and small molecules. Its compatibility with an extensive range of mobile phases adds to its versatility, ensuring seamless integration into your research and analysis workflows.

Bid farewell to salts and contaminants with the MassPREP Micro Desalting Column's high-performance on-line desalting capabilities. Witness the improvement in ionization efficiency and sensitivity of your analytes, enhancing the overall quality of your LC-MS measurements and use of lab equipment.

Whether you're engaged in peptide analysis, protein analysis, or small molecule analysis, this column delivers outstanding peak shape and resolution, even for closely related compounds, thanks to its phenyl stationary phase. Expect nothing less than accurate and reliable results, even in the most challenging separations. These columns are designed for use alongside the Emitter, Picotip, Pre-cut, 5/pk.

Adding to its ease of use, the MassPREP Micro Desalting Column is designed for hassle-free maintenance, saving you valuable time in your analytical endeavors. More than just a single-pack format, the MassPREP Micro Desalting Column opens doors to an extensive array of applications, including environmental analysis, pharmaceutical analysis, and food and beverage analysis. Embrace its power and versatility to unlock new possibilities in your research and analysis pursuits.

The MassPREP Micro Desalting Column is your gateway to improved LC-MS performance. Say hello to superior peak shape, enhanced sensitivity, and efficient desalting, all in one package. Don't miss the chance to experience the transformative capabilities of this column—order your MassPREP Micro Desalting Column today and elevate your LC-MS analysis to unprecedented heights.

What is the best way to store the MassPREP Micro Desalting Column?

To store the column overnight, be sure to continuously flush the column with the mobile phase at a slow flow. If the column isn’t going to be used for several days, store it in 50% acetonitrile without any eluent additives. Do not store in buffered elements and completely seal the stored column to prevent evaporation and drying.