XSelect CSH C18 Column, 130Å, 3.5 µm, 4.6 mm X 150 mm, 1/pk
As a part of the continued innovation around UPLC columns, Waters has introduced Charged Surface Hybrid (CSH) Technology. This new phase of particle technology allows superior peak shape for basic compounds, enhanced loading capacity, improved batch to batch reproducibility, rapid column re-equilibration after changing mobile phases, and superior stability at low pH. To produce these results, Waters starts with the unbonded, efficient, rugged BEH particle, then applies controlled surface charge to the particle surface, and finally functionalizes using the appropriate bonded chemical phase. This technology is available to scientists in the XSelect CSH C18 Column.
XSelect CSH C18 columns were designed with the same priorities as other families of UPLC and HPLC columns, including the wide selectivity range offered by Waters’ proprietary methods. The XSelect CSH C18 column offers method development scientists this wide range of selectivities of any modern columns without compromising any important performance attributes like peak TFA shape for basic compounds, low column bleed, excellent reproducibility, ultra-efficiency, and seamless transferability between different particle sizes and column formats.
When CSH Technology is combined with the analytical method capability of UPLC technology can particularly benefit isolation and purification scientists, as these columns offer the highest loading of basic compounds separated under low pH conditions that are often used in these applications. This allows the use of a narrower, lower volume preparative column, reducing solvent consumption and reaction volume.
With built-in scalability, scientists are able to benefit from the selectivity, loadability, and scalability of the CSH technology without sacrificing the throughput, sensitivity, and transferable analytical-scale method development of UPLC technology.
All XSelect CSH C18 Column material is tested chromatographically with acidic, basic, and neutral analytes. Results are held to narrow specification ranges in order to ensure excellent and reproducible performance.
Shop for lab equipment and explore other related products on our website, such as the XSelect CSH C18 Method Validation Kit, 130Å, 3.5 µm, 4.6 mm X 150 mm, 3/pk.
