Waters offers a comprehensive range of analytical system solutions, software, and services for scientists. Liquid Chromatography. Mass Spectrometry. Waters is the leading provider of lab equipment, supplies and software for scientists across the world. Easily research and order everything your lab needs! Waters offers a comprehensive range of analytical system solutions, software, and services for scientists. Liquid Chromatography. Mass Spectrometry. Waters is the leading provider of lab equipment, supplies and software for scientists across the world. Easily research and order everything your lab needs!
SKU: 186005297 ACQUITY UPLC CSH C18 Column, 130Å, 1.7 µm, 2.1 mm X 100 mm, 1/pk
ACQUITY CSH C18 columns were designed to provide alternate selectivity compared to other reversed-phase UPLC columns. These ultra-efficient columns overcome peak shape asymmetry and poor loading capacity for basic compounds, column bleed, and rapid mobile-phase re-equilibration.
ACQUITY UPLC CSH C18 Column, 130Å, 1.7 µm, 2.1 mm X 100 mm, 1/pk
When you are searching for lab equipment that provides excellent peak shape, high efficiency, and loading capacity for basic compounds while using acidic, low ionic strength mobile phases, the ACQUITY UPLC CSH C18 columns are designed for your needs. Offering alternate selectivity compared to other reversed-phase UPLC columns, these are ultra-efficient and overcome peak shape asymmetry and poor loading capacity for basic compounds, column bleed, and rapid mobile phase re-equilibration. Methods development scientists in all applications can benefit from the widest range of selectivities available in any modern LC columns.
These columns feature Waters’ new and innovative Charged Surface Hybrid (CSH) technology, enabling increased loading capacity and rapid column re-equilibration after changing mobile phase pH. CSH Technology begins with the ethylene bridged hybrid (BEH) particle, which is rugged and efficient, and then applies controlled surface charge to add reproducible low-level charge to the particle surface. This is then functionalized with the appropriate bonded phase chemistry, including bonding and end-capping. This transformative technology combination offers superior peak shape for base compounds, improved batch to batch reproducibility, and excellent stability at low pH.
CSH Technology provides TFA peak shape performance without the use of TFA and its associated disadvantages. Instead, improved peak shape performance is achieved using an MS-friendly mobile phase additive such as formic acid, which does not exhibit the lingering chromatographic effects of an ion-pairing agent. This facilitates straightforward and faster method development.
All ACQUITY CSH packing materials are created specifically for use with the ACQUITY UPLC System and all manufacturing is done in a cGMP, ISO 9001 certified manufacturing facility, using ultra-pure reagents. Each batch is tested chromatographically with acidic, basic, and neutral analytes, with results held to narrow specification ranges that ensure excellent, reproducible performance. Optimize confidence in your results every time by also utilizing the Neutrals QC Reference Material in a wide variety of separation methods.
What Is cGMP Certified?
cGMP stands for the Current Good Manufacturing Practice regulations, which are enforced by the FDA. This provides for systems that assure proper design, monitoring, and control of manufacturing processes and facilities. Adherence to these guidelines is important as it assures the identity, strength, quality, and purity of drug products through controlled manufacturing operations.
Regulations include strong quality management systems, appropriate quality raw materials, robust operating procedures, investigations of quality deviations, and reliable testing laboratories. When put into practice properly, this prevents contamination, deviations, failures, and errors, allowing drug products to meet their quality standards.
