Chemistry |
Phenyl |
Separation Mode |
Reversed Phase |
Particle Substrate |
Hybrid |
pH Range Min |
1 pH |
pH Range Max |
11 pH |
Maximum Pressure |
6000 psi (415 Bar) |
Endcapped |
Yes |
Bonding Technology |
Phenyl-Hexyl |
Silanol Activity |
Low |
Particle Shape |
Spherical |
Particle Size |
5 µm |
Endfitting Type |
Waters |
Pore Size |
130 Å |
Format |
Column |
Surface Area |
185 |
System |
HPLC |
Particle Technology |
CSH |
USP Classification |
L11 |
Inner Diameter |
4.6 mm |
Length |
250 mm |
Carbon Load |
14 % |
UNSPSC |
41115709 |
Brand |
XSelect |
Product Type |
Columns |
Units per Package |
1 pk |
XSelect CSH Phenyl-Hexyl Column, 130Å, 5 µm, 4.6 mm X 250 mm, 1/pk
Benefit from an alternative analyte selectivity compared to traditional reversed-phase columns by using the XSelect CSH Phenyl-Hexyl Column, which is a valuable tool for method development. The lab equipment leverages a trifunctionally bonded C6 phenyl-ligand is a robust, low bleed sorbent that selectively retains polyaromatic compounds through pi-pi interactions. In comparison to the fluorinated phenyl columns available in the market, the Waters XSelect CSH Phenyl-Hexyl Column places more emphasis on reversed-phase interactions versus those of a secondary Lewis-base interaction.
To get exceptional separation performance, robustness, and throughput for HPLC assays while being fully compatible with all HPLC, UPLC, and UHPLC technologies, opt for the XSelect CSH Phenyl-Hexyl Column. As opposed to core-shell columns, the XSelect CSH Phenyl-Hexyl Column gives you outstanding performance and equivalent backpressure. In addition to this, the analytical column is able to provide improved loading capacity and particle size scalability inherent in fully-porous particle columns. The XSelect CSH Phenyl-Hexyl Column incorporated the next evolution of particle technology, the Charged Surface Hybrid (CSH) technology. CSH is used to significantly improve all facets of liquid chromatography performance in acidic, low ionic strength mobile phases. This makes the XSelect CSH Phenyl-Hexyl Column a crucial piece of lab equipment to invest in.
Leverage maximum method development freedom, especially when using low pH mobile phases by using the XSelect CSH Phenyl-Hexyl Column, as it has been designed to maximize selectivity differences. The non-end-capped XSelect CSH Phenyl-Hexyl Column offers enhanced retention of acidic compounds, while its ultra-low dispersion hardware packing enables outstanding separation performance, robustness, and throughput for HPLC assays while enabling a seamless transition path toward UPLC adoption.
The XSelect CSH Column listed here offers a wide operating pH range of 1-11. It is designed to analyze particles sized 5 µm, pore size 130 Å, while withstanding pressures of up to 6,000 psi (415 Bar). The product is delivered as a single unit per pack.
To shop for lab equipment and find products that can work in conjunction with the listing here, order our catalog or browse through the Waters online store.
Waters recommends that you also invest in the XSelect CSH Phenyl-Hexyl VanGuard Cartridge, 130Å, 5 µm, 3.9 mm X 5 mm, 3/pk, in order to prolong the lifetime of your analytical column.
Why Are Phenyl Columns Used?
Phenyl Columns can be successfully used to separate positional isomers, tocopherols, flavonoids, polynuclear aromatics, nitroaromatic compounds, active pharmaceutical ingredients (APIs), and related compounds. Early phenyl columns contained short alkyl phenyl ligands covalently bound to the silica surface.