Chemistry |
HILIC |
Separation Mode |
Hydrophilic Interaction (HILIC) |
Particle Substrate |
Silica |
pH Range Min |
1 pH |
pH Range Max |
5 pH |
Temperature Limits |
45 C |
Maximum Pressure |
18000 psi (1240 Bar) |
Endcapped |
No |
Silanol Activity |
High |
Particle Shape |
Spherical |
Particle Size |
1.6 µm |
Endfitting Type |
Parker-style |
Pore Size |
90 Å |
Format |
Column |
Surface Area |
100 |
System |
UHPLC, UPLC |
Particle Technology |
Solid Core |
USP Classification |
L3 |
Inner Diameter |
2.1 mm |
Length |
100 mm |
eCord |
Yes |
UNSPSC |
41115709 |
Brand |
CORTECS |
Product Type |
Columns |
Units per Package |
1 pk |
CORTECS HILIC Column, 90Å, 1.6 µm, 2.1 mm X 100 mm, 1/pk
Achieve high levels of efficiency and performance whether you are resolving complex mixtures or maintaining resolution while increasing throughput using the CORTECS HILIC Column. When compared to traditional C18 columns, the CORTECS HILIC Column offers orthogonal selectivity. It is a high-efficiency column based on a solid-core particle that is designed to retain extremely polar analytes, making it a crucial piece of lab equipment.
Depend on the CORTECS HILIC Column to deliver faster separations for greater throughput. The lab equipment uses the Hydrophilic Interaction Chromatography (HILIC) mode that has been developed to retain polar compounds where reversed-phase may not be able to by using unbonded solid-core particles. The column offers excellent retention and stability. In contrast to reversed-phase chromatography, which uses a highly aqueous mobile phase for retention of polar analytes, the HILIC uses mobile phases with a high concentration of organic solvent. This makes it directly compatible with SPE eluates, which streamlines sample preparation for higher throughput. The presence of a higher concentration of organic solvent enables more effective desolvation of analytes in the MS source, resulting in improved MS response and sensitivity.
The CORTECS HILIC Column is based on solid-core particles, which give better performance by lowering each of the three terms of the van Deemter equation. The A term is lowered as the solid core particles pack more uniformly. The B term is lowered as the solid core particles exhibit lower particle porosity which reduces axial diffusion. They lower the C term as their solid core improves heat transfer, reducing radial temperature gradients.
All Waters equipment is manufactured to the highest standards under strict and controlled environments to ensure that you receive only the best quality products.
Shop for lab equipment directly from us through our online shop or catalog. Using either of the mediums, you can also reach out to a member of our staff with any queries or concerns you may have regarding our products.
Also read about the CORTECS HILIC VanGuard Pre-column, 90Å, 1.6 µm, 2.1 mm X 5 mm, 3/pk, which is designed to protect your column from harm and extend its lifetime by removing unwanted particulate matter from the mobile phase.
What Do Polar Solvents Dissolve?
Polar/ionic solvents dissolve polar/ionic solutes, and non-polar solvents dissolve non-polar solutes.