BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 1 mm X 50 mm, 1/pk

For IgG monoclonal antibody analysis of mAb fragment analysis to be successful, you need a chromatography column that can overcome difficult chromatographic conditions with ease. Luckily for you, the BioResolve RP mAb Polyphenyl Column does exactly that and so much more. From the moment you perform mAb separations with this flexible yet rugged column, you’ll notice an entire world of difference in sensitivity, chromatographic resolution and throughput. Plus, this column can be used on all UHPLC, UPLC and HPLC systems, so you can easily perform method transfer. The BioResolve RP mAb Polyphenyl Column even offers improved sample loading capabilities. Tell your lab manger that you want this mAb analysis tool at your control now, or order your own and have it shipped directly to you.

What makes the BioResolve RP mAb Polyphenyl Column so unique?
For one, it offers the low hydrophobicity needed to perform reverse-phase analysis of IgG monoclonal antibodies and their fragments. But even more, the superficially porous silica particles in the column are functionalized with a novel polyphenyl bonding process that makes this column uniquely suited to separate mAbs and their fragments. And if you’re wondering about carryover effects, rest easy knowing this column offers minimal injection-to-injection carryover for increased confidence in analyses. What’s more, each and every BioResolve RP mAb Polyphenyl Column must undergo a strict QC process with NIST-based mAb standards before being packed and shipped. This way we can ensure you only receive our best-performing chromatography columns right out of the box.

One major thing you should always be aware of when performing reversed-phase analysis of monoclonal antibodies is column contamination. Although proper sample purification protocols remove many of the contaminants inherent in a sample, there could still be particulate contaminants lingering in the mobile phase stream. To protect your column from those contaminants, we recommend adding the BioResolve RP mAb Polyphenyl VanGuard Cartridge to your analytical workflow. This cartridge is reusable and installs seamlessly between the mobile phase injector and analytical column to provide enhanced protection from the elements.

Before checking out with your BioResolve RP mAb Polyphenyl Column, make sure to browse all of the other incredible products and resources available at Waters. We have everything to help make your lab more efficient and profitable, so shop lab equipment to discover everything we have to offer.