bioresolve scx mab long column

SKU: 186009056
BioResolve SCX mAb Column, 3µm, 2.1 mm X 100 mm, 1/pk

BioResolve SCX mAb Column | 2.1 x 100mm | 186009056


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Product Description

BioResolve SCX mAb Column, 3 µm, 2.1 mm x 100 mm corrosion-resistant columns which contain non-porous, polymer-based particles grafted with a rigorously-optimized, multi-component network of negatively charged sulfonic acid ligands. This innovative column technology, delivers reproducible, high-resolution, charged-based separations of mAbs and other proteins in both LC and LC-MS applications using robust salt or pH gradient methods. Each batch is specifically QC tested using Waters mAb Charge Variant Standard (p/n: 186009065) to help ensure consistent performance.

Note: p/n: 176004344 contains above plus one vial of the mAb Charge Variant Standard (p/n: 186009065)

Suggested Use: Charge Variant Analysis

Specifications

  • pH Range Min

    3 pH

  • Temperature Limits

    60 C

  • Maximum Pressure

    10000 psi (689 Bar)

  • Bonding Technology

    SCX

  • Particle Shape

    Spherical

  • Particle Size

    3 µm

  • QC Tested

    Protein

  • Format

    Column

  • System

    HPLC, UHPLC, UPLC

  • USP Classification

    L34

  • Inner Diameter

    2.1 mm

  • Length

    100 mm

  • eCord

    Yes

  • UNSPSC

    41115709

  • Application

    Protein

  • Brand

    BioResolve

  • Product Type

    Columns

  • Units per Package

    1 pk

Product Support

Documents

Documents



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BioResolve SCX mAb Column, 3µm, 2.1 mm X 100 mm, 1/pk

To overcome the monoclonal antibody separation challenges inherent in the SCX analysis of charge variants, you need an LC-MS instrument that’s both rigid and flexible. Luckily for you, you get that and so much more when you add the BioResolve SCX mAb Column to your lab’s toolkit. At the core of this column is a group of non-porous, polymeric particles that are grafted onto a multi-component network of negatively charged sulfonic acid ligands to provide a unique solution for the LC-MS or LC analysis of mAbs using robust salt or pH gradient methods. What’s more, you can use this column on all UHPLC, UPLC and HPLC systems, and method transfer is made much easier with enhanced sample loading capabilities provided by this column. Want the ability to reliably separate, with accurate charge variant quantitation, a wide range of mAbs?
Purchase the BioResolve SCX mAb Column now, or tell your lab manager that you want BioResolve application-specific technology at your command.

The charge-variant analysis of monoclonal antibodies is a critical drug quality attribute for biological separation scientists to understand. On one hand, optimal diffusion kinetics and pressure tolerance are prioritized thanks to the BioResolve SCX mAb Column, giving you the separation power and stability needed for this chosen application. What’s more, the non-porous, polymeric particles work to reduce analyte band spread and enhanced mAb separations while doing so. You’ll find that the BioResolve SCX mAb Column contains all of the essential features for SCX analyses to be successful and then some. Simply add the BioResolve SCX mAb Column to your cart and have it shipped directly to your lab today.

Each and every BioResolve SCX mAb Column must undergo a strict QC process involving NIST-based mAb standards before being packed and shipped to you. That’s why we’ve included a free vial of the mAb Charge Variant Standard with this column. You can use this standard to test your LC-MS column or other LC-MS systems for proper performance before separations occur.

Protecting your BioResolve SCX mAb Column from contamination over time shouldn’t be difficult, especially when you’re following proper sample purification protocols every time. Unfortunately, there could still be particulate contaminants lingering in the mobile phase stream, which is why we’re happy to provide the BioResolve SCX mAb VanGuard FIT Cartridge. This cartridge removes contaminants from the mobile phase stream before they reach your analytical column.

Ready to upgrade your lab for the better?
Before checking out with the BioResolve SCX mAb Column, make sure to shop lab equipment to discover how our other products and resources can help improve your workflows today.

What’s the BioResolve SCX mAb Column’s Maximum Pressure Range?

The BioResolve SCX mAb Column can withstand pressures up to 10,000 PSI.