SKU: 186009057
BioResolve SCX mAb Column with VanGuard FIT, 3 µm, 4.6 mm X 50 mm, 1/pk

BioResolve SCX mAb Columns with VanGuard FIT | 4.6 x 50mm | 186009057


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Product Description

BioResolve SCX mAb Column with VanGuard FIT, 3 µm, 4.6 mm x 50 mm corrosion-resistant columns which contain non-porous, polymer-based particles grafted with a rigorously-optimized, multi-component network of negatively charged sulfonic acid ligands. This innovative column technology, delivers reproducible, high-resolution, charged-based separations of mAbs and other proteins in both LC and LC-MS applications using robust salt or pH gradient methods. Each batch is specifically QC tested using Waters mAb Charge Variant Standard (p/n: 186009065) to help ensure consistent performance. In addition, this offering includes VanGuard Fully Integrated Technology (FIT) that maximizes column life without degrading biomolecule component resolution.

Note: p/n: 176004346 contains above plus one vial of the mAb Charge Variant Standard (p/n: 186009065)

Suggested Use: Charge Variant Analysis

Specifications

  • pH Range Min

    3 pH

  • Temperature Limits

    60 C

  • Maximum Pressure

    10000 psi (689 Bar)

  • Bonding Technology

    SCX

  • Particle Shape

    Spherical

  • Particle Size

    3 µm

  • QC Tested

    Protein

  • Format

    Column

  • System

    HPLC, UHPLC, UPLC

  • USP Classification

    L34

  • Inner Diameter

    4.6 mm

  • Length

    50 mm

  • eCord

    Yes

  • UNSPSC

    41115709

  • Application

    Protein

  • Brand

    BioResolve

  • Product Type

    Columns

  • Units per Package

    1 pk

Product Support

Documents

Documents



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BioResolve SCX mAb Column with VanGuard FIT, 3 µm, 4.6 mm X 50 mm, 1/pk

Accurate charge-variant quantitation may require using robust salts and pH gradient methods, which means you need a column that’s capable of incorporating those conditions with ease. And with the BioResolve SCX mAb Column, you get exactly that and so much more. At the core of this column is a multi-component network of negatively charged sulfonic acid ligands that makes this column uniquely suited for SCX analysis of monoclonal antibodies and other proteins. Plus, if you want to protect your BioResolve SCX mAb Column from contamination, this column comes with VanGuard column protection solutions for exactly that purpose. See how the BioResolve SCX mAb Column can take your biotherapeutic drug analyses to the next level when you add one to your lab’s procurement list or purchase one directly from us.

The VanGuard Fully Integrated Technology (FIT) included with this column is a breakthrough column protection solution that easily and capably upholds mechanical and chemical stability even under the most difficult chromatographic conditions. VanGuard was designed by scientists for scientists, as column contamination is a major obstacle to overcome, especially when rapidly reproducing separations and transferring methods. Although proper sample purification protocols remove many contaminants, they do not account for any contaminants that may be lingering in the mobile phase stream. To meet this consideration, the VanGuard cartridge filters out any contaminants before they reach your analytical column and negatively affect your mAb separations.

Utilizing robust salt and pH gradient methods for SCX analysis of monoclonal antibodies can often provide you with the kind of chromatographic resolution you truly want. To take advantage of this innovative solution, add the BioResolve CX pH Concentrate A and BioResolve CX pH Concentrate B to your lab’s procurement list. Using these buffer concentrates can help you create a pH 5.0 to pH 10.2 gradient for mAb charge variant separations.

After adding the BioResolve SCX mAb Column to your cart, make sure to browse the entire Waters website to see a vast selection of products and resources all designed to help make your lab more efficient and profitable for all. Simply shop lab equipment to see how our offerings can change your own workflows for the better.

Does the BioResolve SCX mAb Column Come with an eCord?

Yes, the BioResolve SCX mAb Column comes with an eCord for connectivity purposes.