BioResolve SCX mAb Column, 3 µm, 4.6 mm x 100 mm, 1/pk

Strong cation-exchange analysis is frequently used to accurately and reliably separate, with charge variant quantitation, a wide array of monoclonal antibodies. But for SCX analysis to be successful, you need a chromatography column that can withstand chromatographic conditions with ease. And to put it bluntly, the BioResolve SCX mAb Column offers that flexibility and rigidity to help you overcome those conditions. And because charge variant analysis of mAbs and other proteins is what this column provides, we offer a solution-based platform for LC-MS users utilizing robust salt and pH gradient methods to upgrade your analyses. See just how essential the BioResolve SCX mAb Column can be to your mAb analytic workflow by purchasing one today, or tell your lab manager that you want this column at your command.

One of the major benefits of owning the BioResolve SCX mAb Column is that the non-porous polymeric particles inside the column work hard to minimize analyte band spread to enhanced mAb separations, which also gives you superior component recovery, peak shape and component resolution. And because we care deeply about how you perform method development with this column, we’ve configured it to exhibit minimal injection-to-injection carryover during method transfer. What’s more, this column is LC system agnostic, which means it can be used on all UHPLC, HPLC and UPLC systems without any added considerations. This way you can achieve high resolution and robust mAb separations time and again.

Protecting your BioResolve SCX mAb Column from contamination should always be a factor in your analytical workflow. In addition to performing proper sample purification protocols, we recommend adding a BioResolve SCX mAb VanGuard Cartridge to your workflow. This guard cartridge actively removes contaminants from the mobile phase stream before they reach your analytical column and foul it. Plus, this cartridge can be used multiple times and can be cleaned the same way you clean your analytical column. For proper column cleaning and regeneration protocols, refer to the BioResolve SCX mAb Column Care and Use Manual.

At Waters, we offer so much more than just BioResolve SCX mAb Columns to help you better understand the biotherapeutic drug development process. We also offer everything you need in your lab to be successful, including quality control reference materials, lab informatics and data management software, as well as solution kits to upgrade your workflow. Shop lab equipment to stock your lab with all of the essentials.