UNSPSC |
41115712 |
Brand |
Oasis |
Product Type |
Solid Phase Extraction |
Units per Package |
30 pk |
Chemistry |
MCX |
Endcapped |
No |
Format |
Vac Cartridge |
Ion Exchange Capacity |
1 meq/gram |
Mass Spec Compatibility |
Yes |
Mode |
Mixed mode |
Particle Size |
60 µm |
Pore Size |
80 Å |
Sorbent Substrate |
Copolymer |
Sorbent Weight |
150 mg |
Water Wettable |
Yes |
pH Range Min |
0 pH |
pH Range Max |
14 pH |
Material |
Polypropylene |
Barrel Size |
6 cc |
Oasis MCX 6 cc Vac Cartridge, 150 mg Sorbent per Cartridge, 60 µm, 30/pk
Designed to overcome the limitations of traditional silica-based mixed-mode SPE sorbents, Oasis MCX 6 cc Vac Cartridge is a strong mixed-mode cation exchange, water-wettable, polymeric sorbent. Oasis MCX is made reproducibly by a novel process that has been patented by Waters. The sorbent offers dual modes of retention – ion exchange and reversed-phase – on a single, clean, stable, high surface area, organic co-polymer that remains stable across the entire pH range.
In addition to the superior pH stability typical of DVB polymers, Oasis MCX 6 cc Vac Cartridge offers a greater binding capacity than silica-based mixed-mode SPE sorbents. With the ability to manipulate pH during development, optimization, and use of SPE methods on mixed-mode sorbents, scientists are able to complete fast and straightforward method development that still offers rugged and robust procedures. These results can be achieved with no analyte breakthrough or loss of recovery as a result of dissolving silica particles at high pH or cleaving bonded phase at low pH.
A typical silica-based mixed-mode sorbent is synthesized in a complex process that is difficult to control, while offering relatively low exchange capacities that range from 0.06-0.2 meq/g. The novel and well-controlled Waters’ production process reproducibly delivers Oasis MCX with 1.0 meq/g of sulfonic acid ion exchange capacity.
The sorbent is delivered in a 6 cc cartridge made from polypropylene and is delivered in packages of 30 cartridges. Oasis MCX 6 cc Vac Cartridges are syringe-barrel type cartridges, designed for use with vacuum manifolds and automated SPE lab equipment. Oasis MCX sorbent is QC tested for performance using analyte recovery and phospholipid removal as benchmarks, and it can be used effectively alongside Waters’ Carbamate Analysis Kit and other high-quality pieces of lab equipment. .
What Advantages Does SPE Offer?
SPE, or solid-phase extraction, offers a range of solutions to address the most common sample preparation concerns among scientists. SPE is an effective tool to eliminate matrix effects like interferences, and enabling sensitive, selective, and robust analysis. Reduction of interferences also lowers method variability and increases MS response, leading to a reduction in ion suppression. Advances in SPE technology and robotic automation have made SPE a cost-effective and time-efficient technique for sample preparation. This improves analytical system performance by extending column lifetime, which reduces downtime and maintenance.