Oasis PRiME HLB 96-well µElution Plate, 3 mg Sorbent per Well, 1/pk

The extremely water-wettable nature of the Oasis PRiME HLB Copolymer enables chromatographers to eliminate the condition and equilibration efforts required when using silica-based and other polymeric sorbents. Other sorbents that aren"t water-wettable do not effectively retain analytes of interest during sample loading, causing a loss of recovery. With Oasis PRiME HLB, valuable sample processing time is saved and costly solvent purchase and disposal is avoided. Since you can choose the sample preparation method that best meets your analytical needs, Oasis PRiME HLB offers simplicity that allows you to integrate it into your laboratory"s workflow without requiring SPE expertise.

With the Oasis PRiME HLB 96-well µElution Plate, not only can you eliminate extra steps, but viscous samples flow more easily through the plate as a result of new and optimized frit and sorbent design. Flow rates are much faster for common matrices like urine, milk, and plasma, and optimal load, wash, and elution flow rates are achieved using less vacuum or positive pressure than other SPE devices. This piece of lab equipment can help achieve highly reproducible sample clean-up with less process complexity across fewer steps.

With the patented 96-well µElution plate design, there is no evaporation or reconstitution necessary due to elution volumes as low as 25 µL and up to a 15 times increase in concentration. These plates are ideal for SPE cleanup and analyte enrichment of sample volumes from 10 µL to 375 µL and are compatible with most liquid-handling robotic systems for automated and reliable high throughput SPE. Oasis PRiME HLB sorbent is also available in the Oasis PRiME HLB 96-well Plate, 10 mg Sorbent per Well, 1/pk with 10 mg of sorbent per well for high throughput and high recovery.

Oasis PRiME HLB 96-well µElution Plate, 3 mg Sorbent per Well, 1/pk FAQs

What are the benefits of using a µElution plate for SPE?
The Oasis PRiME HLB 96-well µElution Plate offers several advantages over traditional solid-phase extraction (SPE) formats, particularly for high-throughput and low-volume sample processing. Its small elution volume (as low as 25 µL) eliminates the need for evaporation, allowing for direct injection into LC-MS/MS systems, which improves sensitivity and reduces sample handling time.

The 96-well format is ideal for automation, enabling simultaneous processing of multiple samples with high reproducibility. Additionally, the µElution design enhances analyte concentration, making it particularly useful for samples with low analyte concentrations. The PRiME HLB sorbent simplifies sample cleanup by removing more phospholipids and matrix interferences than traditional SPE, resulting in cleaner extracts, better analytical performance, and reduced instrument downtime.

What types of analytes can be extracted using this plate?
The Oasis PRiME HLB 96-well µElution Plate is designed for a wide range of analytes, including small molecules, drugs, peptides, and metabolites, making it highly versatile for applications in pharmaceutical, clinical, forensic, food safety, and environmental analysis.

The hydrophilic-lipophilic balance (HLB) sorbent retains both polar and nonpolar compounds, allowing for efficient extraction of acidic, neutral, and basic analytes in a single method. This plate is particularly effective for bioanalytical applications, such as the extraction of drugs from plasma, urine, or serum, due to its ability to remove unwanted matrix components while preserving analyte integrity.

The plate"s ability to handle complex biological and environmental samples with high recovery and reproducibility makes it an excellent choice for laboratories requiring sensitive, high-throughput sample preparation for LC-MS/MS analysis.