Oasis HLB 3 cc Vac Cartridge, 60 mg Sorbent per Cartridge, 30 µm, 100/pk
Achieve robust and reproducible SPE results with simple and innovative methods for sample preparation. As part of the Oasis family of solid-phase extraction products, Oasis HLB uses the patented hydrophilic-lipophilic-balanced reversed-phase sorbent for acids, bases, and neutrals. The first water-wettable, yet hydrophobic, polymeric sorbent significantly changed the practice of SPE across laboratories.
The Oasis HLB universal sorbent is made from a ratio between two monomers to provide superior reversed-phase capacity and a neutral polar "hook", facilitating enhanced retention of polar analytes. These monomers, hydrophilic-N-vinylpyrrolidone and lipophilic divinylbenzene, are combined using Waters" specific formula to ensure excellent results. The water-wettable nature of the sorbent not only provide higher retention and recoveries when sorbent runs dry, preventing the need for additional steps to prevent the drying out of sorbent beds during important steps before sample loading.
As a part of the Oasis HLB family of SPE sorbents, scientists will see stability at pH extremes as well as in a wide range of solvents, an unprecedented retention of polar compounds, and a relative hydrophobic retention capacity that can be 3x above traditional silica-based SPE sorbents like C18. With the sorbent"s higher retention capacity [k], more analytes can be retained with less breakthrough, allowing for improved recovery and reproducibility of your lab"s SPE method, making it an excellent choice for lab equipment in any workspace.
These sorbents are sold in syringe-barrel-type cartridges that are made to be used with vacuum manifolds and automated SPE instruments. Another related product that your scientists may be interested in is the XSelect CSH C18 XP Column, 130Å, 2.5 µm, 2.1 mm X 100 mm, 1/pk.
From Waters" Oasis HLB sorbents to columns and other products, all manufacturing processes are subject to stringent quality control processes that ensure superior batch-to-batch reproducibility. All products are manufactured in Waters IDO 9000 registered facilities that comply with cGMP guidelines.
FAQs About Oasis HLB 3 cc Vac Cartridge, 60 mg Sorbent per Cartridge, 30 µm, 100/pk
1. What makes the Oasis HLB sorbent unique compared to other SPE sorbents?
The Oasis HLB sorbent is unique due to its hydrophilic-lipophilic balance, achieved through its copolymer design of divinylbenzene and N-vinylpyrrolidone. This structure provides dual-mode retention, making it highly versatile for both polar and non-polar compounds. Unlike silica-based sorbents, Oasis HLB is water-wettable, maintaining performance even in low organic solvent conditions. It exhibits exceptional chemical stability and high capacity, ensuring consistent and reliable extractions across a wide range of applications. This makes it ideal for sensitive analytical workflows requiring superior recovery and reproducibility.
2. What are the chemical and pH stability ranges for the Oasis HLB sorbent?
The Oasis HLB sorbent offers excellent chemical and pH stability, supporting a broad pH range of 0 to 14. This robustness enables the sorbent to withstand highly acidic and highly basic conditions, making it suitable for diverse sample matrices and challenging extractions. Additionally, it is compatible with various solvents, including aqueous, organic, and mixed-phase solutions, without compromising its performance or structural integrity.
3. What types of solid-phase extraction (SPE) applications are these cartridges suitable for?
Oasis HLB cartridges are suitable for a wide variety of SPE applications, including pharmaceutical, environmental, clinical, and food analysis. They excel in the extraction of polar and non-polar analytes, such as drugs, metabolites, pesticides, and contaminants, from complex sample matrices like plasma, urine, soil, and water. The dual-mode retention mechanism ensures high recoveries for compounds with varying polarities, while the water-wettable nature allows direct loading of aqueous samples. This versatility makes Oasis HLB cartridges an excellent choice for both qualitative and quantitative workflows, particularly those requiring sensitivity and reproducibility in trace-level analyses.
