Waters offers a comprehensive range of analytical system solutions, software, and services for scientists. Liquid Chromatography. Mass Spectrometry. Waters is the leading provider of lab equipment, supplies and software for scientists across the world. Easily research and order everything your lab needs! Waters offers a comprehensive range of analytical system solutions, software, and services for scientists. Liquid Chromatography. Mass Spectrometry. Waters is the leading provider of lab equipment, supplies and software for scientists across the world. Easily research and order everything your lab needs!
In order to take full advantage of the BEH glycan column, Waters created the 2-aminobenzamide labeled 2-AB Dextran Calibration Ladder Standard to assist glycan profiling. Glycan profile obtained from UPLC-HILIC/FLR systems can be calibrated against the 2AB-labeled dextran ladder and assigned with glucose unit (GU) values. Waters 2-AB labeled Dextran Calibration Ladder is different than the existing commercial offerings. The average molecular weight of the glucose homopolymer is higher (~4,500 Dalton), therefore, the workable GU value range is twice as much as the other dextran ladder standards; the observed GU goes from 2 to 30. This feature improves the large glycan retention time assignment.
Waters designed the 2-aminobenzamide labeled 2-AB Dextran Calibration Ladder Standard to enhance glycan profiling and take full benefit of the BEH glycan column. The 2AB-labeled dextran ladder can be used to calibrate the glycan profile derived from UPLC-HILIC/FLR systems, and glucose unit (GU) values can be assigned. The Waters 2-AB labeled Dextran Calibration Ladder is unlike anything else on the market. The glucose homopolymer has a greater average molecular weight (4,500 Dalton); therefore, the usable GU value range is twice as large as the other dextran ladder standards; the measured GU ranges from 2 to 30. This feature optimizes the assignment of big glycan retention times.
The Dextran Calibration Ladders allow users to connect the whole GlycoWorks Sample Preparation Solution to the Waters ACQUITY UPLC System and the GlycoBase Database Search in a seamless manner. The user can calibrate their equipment based on GU units and be confident in the findings by using the designated standards.
Add the 2-AB Dextran Calibration Ladder to your lab equipment collection. You can find additional products that are compatible with 2-AB Dextran Calibration Ladder, including additional calibration standards, guards, vials, and elution plates from our website. The website enables you to shop for lab equipment, as well as to reach out with any queries you may have. You can direct these queries and concerns to a member of our staff, located in one of our numerous offices located globally.
We also recommend reviewing the 2-AB Glycan Performance Test Standard; The 2-AB Glycan Performance Test Standard is 2-AB labeled Human IgG and is QC verified to contain the components needed to benchmark and evaluate ACQUITY UPLC BEH Glycan, 1.7 µm Columns. It comes in a Waters TruView vial as a lyophilized powder. There is 228 pmol total/vial. It is recommended that this standard be used on a regular basis for benchmarking column and system performance, similar to the QCRM product line.
What Is The Importance Of Chromatography Sensitivity?
Sensitivity is the measurement of the signal output per unit concentration or mass of a substance in the mobile phase as it enters the detector. It is commonly determined by the slope of a linear calibration curve. In concentration-sensitive detectors, sensitivity is defined as the ratio of peak height to the analyte concentration within the peak. In mass-flow-sensitive detectors, it is expressed as the ratio of peak height to the unit mass of the analyte. To ensure that sensitivity is a distinct performance characteristic, it should only depend on the chemical measurement process and not on scale factors. The ability to detect or quantify an analyte is influenced by various instrumental and chemical factors.
