IonHance CX-MS pH Concentrate A, pH 5 in MS Certified LDPE Container (10X Concentrate)

Designed alongside the BioResolve SCX columns, the IonHance CX-MS pH 10X Concentrate A, in MS Certified LDPE Container, was carefully optimized for use in creating a gradient for LC/MS analysis of mAb charge variant separations.

Mobile-phase additives, such as strong acids or buffers, are commonly used to increase analyte retentivity and peak form in liquid chromatography. To limit background contribution and ensure data quality in MS applications, high-purity mobile-phase additives must be introduced as a mandatory step.

IonHance modifiers are employed for reversed-phase separations of proteins, peptides, and small compounds in LC and LC-MS methods. The IonHance modifiers were created with attention to help achieve minimal metal content and good quality standards. The IonHance CX-MS pH Concentrate A, which contains the IonHance modifiers, is used in conjunction with the BioResolve SCX columns to improve sensitivity, retentivity, and peak shape for even the most difficult separations.

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You may also be interested in the BioResolve SCX mAb Column with VanGuard FIT 3 µm, 2.1 mm x 100 mm, 1/pk. BioResolve SCX mAb columns are 3 μm corrosion-resistant columns that comprise non-porous polymer-based particles grafted with a multi-component network of negatively charged sulfonic acid ligands that has been thoroughly tuned. Using robust salt or pH gradient approaches, this unique column technology enables consistent, high-resolution, charged-based separations of mAbs and other proteins in both LC and LC-MS applications. This package also incorporates VanGuard Fully Integrated Technology (FIT), which extends the life of the column without compromising biomolecule component resolution.