Bioseparations Columns

Bioseparations Columns

Characterize today’s biotherapeutics and biosimilars with Waters ion-exchange, size-exclusion, reversed-phase, hydrophobic-interaction, and hydrophilic-interaction chromatography columns.

Characterize today’s biotherapeutics and biosimilars with Waters ion-exchange, size-exclusion, reversed-phase, hydrophobic-interaction, and hydrophilic-interaction chromatography columns.

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Transform your biotherapeutic characterization with Waters innovative HPLC, UHPLC, and UPLC chemistries, designed and quality control tested to meet bioseparations needs, whether you are looking at amino acids, peptides, proteins, oligonucleotides, or glycans with superior component resolution and reproducibility.


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  • XSelect Premier Columns
    XSelect Premier Columns

    Discover XSelect Premier UHPLC Columns designed to improve peak shape and maximize selectivity while mitigating unwanted analyte/surface interactions.

  • Gene-Based Therapeutics (GTx) Columns
    Gene-Based Therapeutics (GTx) Columns

    Analyze gene therapeutics to learn about the potency and safety of your sample with Waters Gene Therapeutics (GTx) Size-Exclusion Chromatography (SEC) Columns, designed to provide accurate, high-throughput data.

  • SEC Columns
    SEC Columns

    Analytical size-exclusion chromatography columns are ideal for aggregate, monomer, and fragment analysis. Separate biomolecules by size in solution with Waters SEC Columns.

  • ACQUITY UPLC Columns
    ACQUITY UPLC Columns

    Discover how to achieve increases in LC efficiency, resolution, sensitivity, accuracy, speed, and reliability with ACQUITY sub-2-μm UPLC particle columns.

  • XBridge Columns
    XBridge Columns

    Experience XBridge HPLC and UHPLC Columns, ideal for methods development at extreme temperatures and mobile-phase pH. Explore XBridge BEH Column chemistries today.

  • XSelect Columns
    XSelect Columns

    Get superior selectivity and peak shape for basic compounds with XSelect HPLC and UHPLC Columns. Discover our CSH and high-strength silica columns. Visit today.

  • ACQUITY Premier Columns
    ACQUITY Premier Columns

    Achieve increases in sensitivity and analyte recovery while reducing column passivation time and mitigating unwanted analyte/surface interactions with ACQUITY Premier Columns.

  • AccQ•Tag Columns for Amino Acid Analysis
    AccQ•Tag Columns for Amino Acid Analysis

    Experience accurate and reproducible UPLC, UHPLC, and HPLC amino acid analysis with Pico•Tag, AccQ•Tag, and AccQ•Tag Ultra C18 Columns and Derivatization Kits.

  • Advanced Purification Glass Columns
    Advanced Purification Glass Columns

    Meet protein purification needs with Advanced Purification glass columns with silica, polymer or soft gel packings, designed for analytical & preparative LC instruments.

  • BioResolve Columns
    BioResolve Columns

    Streamline analytical challenges associated with mAb characterizations and associated biotherapeutic drug separations with BioResolve Columns.

  • BioResolve Premier Columns
    BioResolve Premier Columns

    Increase bioanalysis recovery, reproducibility, and enhance LC and LC-MS sensitivity with Waters BioResolve Premier Columns, reversed-phase ion exchange columns designed for bioanalysis applications

  • BioSuite Columns
    BioSuite Columns

    Ideal for the isolation, analysis, and characterization of proteins and peptides, BioSuite Columns offer multiple chemistries: C18, cation and anion-exchange, SEC, & Phenyl.

  • Delta-Pak Columns
    Delta-Pak Columns

    Separate and isolate peptides, proteins, and natural products with Delta-Pak HPLC Columns for large molecule separations.

  • Enzymate Pepsin Column
    Enzymate Pepsin Column

    Achieve fast, efficient, and reproducible online protein digestion with shorter sample preparation time with the Enzymate BEH Pepsin Column. Explore now.

  • GTxResolve Premier BEH Amide Columns
    GTxResolve Premier BEH Amide Columns

    Develop high resolution, ion-pairing free analysis methods for synthetic oligonucleotides, digested nucleic acids, and capsid proteins with GTxResolve Premier BEH Amide Columns.

  • GTxResolve SEC Columns
    GTxResolve SEC Columns

    Reliable and robust critical quality attribute analysis of aggregates for Lipids nanoparticles (LNPs), nucleic acids, and viral vectors using GTxResolve columns.

  • Gen-Pak FAX Columns
    Gen-Pak FAX Columns

    Perform complicated synthesis, analysis and other HPLC assays with Gen-Pak FAX Anion-Exchange Columns. Explore our Gen-Pak oligonucleotide synthesis columns now.

  • MassPREP On-Line Desalting Cartridges
    MassPREP On-Line Desalting Cartridges

    For a quick, easy and reproducible protocol for desalting acidic, basic and large globular proteins, choose MassPREP On-line Desalting Cartridges.

  • MaxPeak Premier OBD Preparative Columns
    MaxPeak Premier OBD Preparative Columns

    Minimize non-specific adsorption (NSA) inherent to preparative chromatography while yielding high-purity results with MaxPeak Premier OBD Preparative Columns.

  • MaxPeak Premier Protein SEC Columns
    MaxPeak Premier Protein SEC Columns

    Enhance your workflow with MaxPeak Premier Protein SEC Columns, size-exclusion chromatography columns for the characterization of proteins and peptides.

  • Nano and MicroFlow LC-MS Columns
    Nano and MicroFlow LC-MS Columns

    Meet high efficiency and selectivity requirements for complex peptide and protein separations with Waters nano and microflow LC-MS Columns.

  • Protein-Pak Columns
    Protein-Pak Columns

    Achieve high-quality LC-based analyses & lab scale purifications of peptides and proteins with Protein-Pak IEX & HIC Columns, designed for use on HPLC and UPLC systems.

  • Symmetry HPLC Columns
    Symmetry HPLC Columns

    Get predictable analytical performance and ensure batch-to-batch reproducibility with high purity silica-based Symmetry HPLC Columns.

  • XBridge Premier Columns
    XBridge Premier Columns

    Experience XBridge Premier UHPLC Columns, designed to operate under extreme temperatures and mobile-phase pH while mitigating unwanted analyte/surface interactions.