Bioseparations Columns
Bioseparations Columns
Characterize today’s biotherapeutics and biosimilars with Waters ion-exchange, size-exclusion, reversed-phase, hydrophobic-interaction, and hydrophilic-interaction chromatography columns.
Characterize today’s biotherapeutics and biosimilars with Waters ion-exchange, size-exclusion, reversed-phase, hydrophobic-interaction, and hydrophilic-interaction chromatography columns.


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Transform your biotherapeutic characterization with Waters innovative HPLC, UHPLC, and UPLC chemistries, designed and quality control tested to meet bioseparations needs, whether you are looking at amino acids, peptides, proteins, oligonucleotides, or glycans with superior component resolution and reproducibility.
Explore our bioseparations column solutions
Explore our bioseparations column solutions
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- XSelect Premier ColumnsDiscover XSelect Premier UHPLC Columns designed to improve peak shape and maximize selectivity while mitigating unwanted analyte/surface interactions.
- Gene-Based Therapeutics (GTx) ColumnsAnalyze gene therapeutics to learn about the potency and safety of your sample with Waters Gene Therapeutics (GTx) Size-Exclusion Chromatography (SEC) Columns, designed to provide accurate, high-throughput data.
- SEC ColumnsAnalytical size-exclusion chromatography columns are ideal for aggregate, monomer, and fragment analysis. Separate biomolecules by size in solution with Waters SEC Columns.
- ACQUITY UPLC ColumnsDiscover how to achieve increases in LC efficiency, resolution, sensitivity, accuracy, speed, and reliability with ACQUITY sub-2-μm UPLC particle columns.
- XBridge ColumnsExperience XBridge HPLC and UHPLC Columns, ideal for methods development at extreme temperatures and mobile-phase pH. Explore XBridge BEH Column chemistries today.
- XSelect ColumnsGet superior selectivity and peak shape for basic compounds with XSelect HPLC and UHPLC Columns. Discover our CSH and high-strength silica columns. Visit today.
- ACQUITY Premier ColumnsAchieve increases in sensitivity and analyte recovery while reducing column passivation time and mitigating unwanted analyte/surface interactions with ACQUITY Premier Columns.
- AccQ•Tag Columns for Amino Acid AnalysisExperience accurate and reproducible UPLC, UHPLC, and HPLC amino acid analysis with Pico•Tag, AccQ•Tag, and AccQ•Tag Ultra C18 Columns and Derivatization Kits.
- Advanced Purification Glass ColumnsMeet protein purification needs with Advanced Purification glass columns with silica, polymer or soft gel packings, designed for analytical & preparative LC instruments.
- BioResolve ColumnsStreamline analytical challenges associated with mAb characterizations and associated biotherapeutic drug separations with BioResolve Columns.
- BioResolve Premier ColumnsIncrease bioanalysis recovery, reproducibility, and enhance LC and LC-MS sensitivity with Waters BioResolve Premier Columns, reversed-phase ion exchange columns designed for bioanalysis applications
- BioSuite ColumnsIdeal for the isolation, analysis, and characterization of proteins and peptides, BioSuite Columns offer multiple chemistries: C18, cation and anion-exchange, SEC, & Phenyl.
- Delta-Pak ColumnsSeparate and isolate peptides, proteins, and natural products with Delta-Pak HPLC Columns for large molecule separations.
- Enzymate Pepsin ColumnAchieve fast, efficient, and reproducible online protein digestion with shorter sample preparation time with the Enzymate BEH Pepsin Column. Explore now.
- GTxResolve Premier BEH Amide ColumnsDevelop high resolution, ion-pairing free analysis methods for synthetic oligonucleotides, digested nucleic acids, and capsid proteins with GTxResolve Premier BEH Amide Columns.
- GTxResolve SEC ColumnsReliable and robust critical quality attribute analysis of aggregates for Lipids nanoparticles (LNPs), nucleic acids, and viral vectors using GTxResolve columns.
- Gen-Pak FAX ColumnsPerform complicated synthesis, analysis and other HPLC assays with Gen-Pak FAX Anion-Exchange Columns. Explore our Gen-Pak oligonucleotide synthesis columns now.
- MassPREP On-Line Desalting CartridgesFor a quick, easy and reproducible protocol for desalting acidic, basic and large globular proteins, choose MassPREP On-line Desalting Cartridges.
- MaxPeak Premier OBD Preparative ColumnsMinimize non-specific adsorption (NSA) inherent to preparative chromatography while yielding high-purity results with MaxPeak Premier OBD Preparative Columns.
- MaxPeak Premier Protein SEC ColumnsEnhance your workflow with MaxPeak Premier Protein SEC Columns, size-exclusion chromatography columns for the characterization of proteins and peptides.
- Nano and MicroFlow LC-MS ColumnsMeet high efficiency and selectivity requirements for complex peptide and protein separations with Waters nano and microflow LC-MS Columns.
- Protein-Pak ColumnsAchieve high-quality LC-based analyses & lab scale purifications of peptides and proteins with Protein-Pak IEX & HIC Columns, designed for use on HPLC and UPLC systems.
- Symmetry HPLC ColumnsGet predictable analytical performance and ensure batch-to-batch reproducibility with high purity silica-based Symmetry HPLC Columns.
- XBridge Premier ColumnsExperience XBridge Premier UHPLC Columns, designed to operate under extreme temperatures and mobile-phase pH while mitigating unwanted analyte/surface interactions.