Xevo G3 QTof

Xevo G3 QTof

Complete coverage for confident characterization

Complete coverage for confident characterization

Maximize sample information for your analytes from detailed characterization to accurate quantitation with the Xevo G3 QTof, which enables complete confidence in your results.

The latest generation of the Xevo product line extends the simplicity and range of characterization, from challenging small molecules to complex biotherapeutics. Updates to the ion optics design provide consistent robustness and performance, with incorporation of core technology for comprehensive quantitation capabilities. Centered around an expanding array of informatics tools, the Xevo G3 QTof has your lab covered.

Xevo-G3-QT-complete Xevo G3 QTof

Overview

  • Ultimate performance: Ensure maximum coverage of analytes, with improved transmission of low mass labile species, while still excelling in traditional biopharmaceutical workflows and addressing emerging needs to characterize new modalities. 
  • Connected productivity: Harmonize workflows across development, manufacturing and monitoring/quality control (QC) with the waters_connect ecosystem, Xevo G3 QTof, and BioAccord System with ACQUITY Premier. 
  • Extended flexibility: Improve quantitative capabilities, with wider inter- and intra-spectrum dynamic range for comprehensive quantitative/qualitative analysis, ideal for screening and targeted applications. 
  • Unquestioned confidence: Achieve consistent data quality and reproducibility to maintain performance and productivity over a longer time period, with updated ion optics.

Recommended Use: Characterize and quantify a diverse set of molecules on a single, analytical workhorse.


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Ultimate performance for a range of analytes

Demand more from your analytical systems to extend the capabilities of your lab. The Xevo G3 QTof incorporates new technology building blocks that improve the ability to characterize complex biologics (with the inclusion of a m/z 16,000 calibration range and tailored informatics) while enhancing the analysis of challenging small molecules (with updates to the ion optics and detection system to maximize transmission and dynamic range). The Xevo G3 QTof, equipped with the StepWave XS, efficiently transmits low mass, labile species – enabling you to increase compound coverage and analytical fidelity.


Connected productivity for harmonized workflows

Harmonizing workflows across development, manufacturing, and QC is key to ensuring lab productivity. The Xevo G3 QTof is ideal for characterizing biomolecules and processes before transitioning to dedicated attribute monitoring assays on the Xevo G3 QTof or BioAccord System with ACQUITY Premier. The waters_connect ecosystem offers seamless, compliance-ready workflows to understand and monitor biotherapeutic variation. Systems and users are connected through waters_connect with security-controlled access, full data traceability, and the operational efficiency and scalability of networked deployment. 


Delivering qualitative and quantitative performance

Maximize system usage with a flexible multifunctional instrument that delivers high-quality quantitative and qualitative data sets. The Xevo G3 QTof has evolved to specifically address these needs, with updates to core technology delivering up to 5 orders of linear dynamic range for targeted analysis.

For untargeted and screening experiments, the Xevo G3 QTof can detect and quantify components of interest in the most challenging complex matrices with up to 4x increase in-spectrum dynamic range.


Unquestioned confidence with consistent robustness and reproducibility

Instrument stability and uptime is an unquestioned necessity in a fast-paced, high-throughput environments. The evolved design of the Xevo G3 QTof has been engineered to deliver consistent robustness and reproducibility, maintaining performance and productivity over a longer time period. With updated ion optics design and optimized ion beam conditioning, the Xevo G3 QTof is a true analytical workhorse that reliably and routinely delivers high-quality data.


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Xevo G3 QTof

The Xevo G3 QTof is at the forefront of mass spectrometry technology, providing unmatched performance and reliability for the comprehensive characterization and quantitation of your analytes. This cutting-edge instrument is designed to maximize sample information, offering detailed characterization and accurate quantitation to ensure complete confidence in your results.

The Xevo G3 QTof represents the latest iteration in the Xevo product line, extending the simplicity and range of characterization from challenging small molecules to complex biotherapeutics. It incorporates a m/z 16,000 calibration range and tailored informatics, enhancing the ability to characterize complex biologics with precision. For small molecule analysis, updates to the ion optics and detection system maximize transmission and dynamic range, improving the accuracy and reliability of results. The inclusion of StepWave XS technology allows for efficient transmission of low mass, labile species, increasing compound coverage and ensuring analytical fidelity.

Productivity in the laboratory is enhanced through harmonized workflows across development, manufacturing, and quality control (QC). The Xevo G3 QTof is specifically designed to excel in characterizing biomolecules and processes before transitioning to dedicated attribute monitoring assays. When coupled with the BioAccord System with ACQUITY Premier, it offers seamless, compliance-ready workflows that facilitate the understanding and monitoring of biotherapeutic variation. The waters_connect ecosystem ensures that systems and users are connected with security-controlled access, full data traceability, and operational efficiency through scalable, networked deployment.

The Xevo G3 QTof sets a new standard for flexibility in mass spectrometry. It offers a wider inter- and intra-spectrum dynamic range for comprehensive quantitative and qualitative analysis, making it ideal for both screening and targeted applications. This multifunctional instrument delivers high-quality data sets, addressing the evolving needs of modern analytical laboratories. For untargeted and screening experiments, the Xevo G3 QTof can detect and quantify components of interest in the most challenging complex matrices, providing up to a 4x increase in the in-spectrum dynamic range.

In high-throughput environments, instrument stability and uptime are critical to maintaining productivity. The Xevo G3 QTof is engineered for consistent robustness and reproducibility, ensuring high performance over extended periods. Its evolved design includes updated ion optics and optimized ion beam conditioning, making the Xevo G3 QTof a reliable analytical workhorse that consistently delivers high-quality data. This reliability translates into unquestioned confidence in your results, whether you are conducting routine analyses or exploring new research frontiers.

The Xevo G3 QTof is the ideal choice for laboratories requiring a versatile and powerful analytical instrument. It is designed to characterize and quantify a diverse set of molecules, from small pharmaceutical compounds to large biotherapeutic proteins. This single, analytical workhorse offers ultimate performance, connected productivity, extended flexibility, and unquestioned confidence, making it an indispensable tool for any modern laboratory aiming to achieve comprehensive and reliable results.

FAQs about the Xevo G3 QTof

What types of samples can the Xevo G3 QTof analyze?

The Xevo G3 QTof is designed to analyze a wide range of samples, from challenging small molecules to complex biotherapeutics. Its advanced ion optics and detection system ensures accurate and comprehensive characterization and quantitation of various analytes.

What are the benefits of the waters_connect ecosystem?

The waters_connect ecosystem offers seamless, compliance-ready workflows, security-controlled access, full data traceability, and operational efficiency through networked deployment. It harmonizes workflows across development, manufacturing, and QC, enhancing lab productivity and connectivity.

How does the Xevo G3 QTof improve lab productivity?

The Xevo G3 QTof enhances lab productivity by providing harmonized workflows across development, manufacturing, and QC. Its seamless integration with the waters_connect ecosystem and BioAccord System with ACQUITY Premier ensures efficient, compliance-ready operations, connecting systems and users for optimal performance and data traceability.

Is the Xevo G3 QTof suitable for both qualitative and quantitative analysis?

Yes, the Xevo G3 QTof offers a wider inter- and intra-spectrum dynamic range, making it ideal for comprehensive quantitative and qualitative analysis. It delivers high-quality data sets for both screening and targeted applications, addressing the evolving needs of modern analytical laboratories.