Automate Metabolism Studies
The MetaboLynx™ XS Application Manager rapidly detects the peaks in your LC/MS & LC/MS/MS sample analysis that result from in vitro or in vivo biotransformation. By automating the data processing, MetaboLynx XS enables rapid metabolite identification.
MetaboLynx XS capabilities include:
- Interrogating LC/MS & LC/MS/MS data for targeted metabolites
- Integration with MassFragmentTM for structural elucidation
- Correlating metabolized sample data with a control sample
- Pinpointing untargeted biotransformations using:
- 3D LC/MS metrics - mass/intensity/retention time
- Exact mass measurement
- Calculated elemental composition
- Isotopic pattern targeting for enhanced selectivity
- PDA data
- Up to 4 auxiliary (analog input) detectors e.g. radiochemical, fluorescence
- Generating and executing method files for automated MS-MS verification of metabolite assignments with:
- Comparison with parent MS/MS
- Flagging of common product ions and neutral losses
- Integrating chromatographic peaks for semi-quantification
- Electronic reporting/distribution of results.
Review Data Locally or Remotely
Through the MetaboLynx XS data browser, you can review locally (or remotely via a secure corporate network) the chromatographic and mass spectroscopic evidence that support each automated metabolic assignment.
Electronic Data Reporting
MetaboLynx XS automatically creates a summary report that you can e-mail directly to a client analyst for review with the MetaboLynx results browser. Or, export your results to Microsoft Excel or Word for customized reports.
