Rapid Analysis of Bisphenols A, B, and E in Baby Food and Infant Formula Using ACQUITY UPLC with the Xevo TQD
BPA is an endocrine disruptor, which can mimic the body’s own hormones and may lead to negative health effects. In 2001, concerns about the estrogenic activity of BPA were raised and several governments released reports questioning the safety of its use in consumer products. Canada became the first country to take action on BPA through their Chemicals Management Plan, listing BPA as a toxic substance.
The United States Food and Drug Administration (FDA) released a report in 2010 expressing some concern regarding BPA exposure of fetuses, infants, and young children, which has prompted further studies into the safety of BPA. A recent European Union directive (EU 2011/8/EU) has banned the use of BPA in infant feeding bottles.
Since the EPA's ban of BPA products targeting the food industry, manufacturers are actively working to identify substitute bisphenols for new epoxy formulation. This application note presents the results for three bisphenols (A, B, and E) in baby food and powdered milk formula. The final optimized method, which requires a robust extraction protocol for targeting trace-level detection, has an analysis time of less than five minutes.
There is potential for extending this methodology to other food products that could come into contact with polycarbonates or epoxy resins.
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