Seamless Integration of Mass Detection into the UV Chromatographic Workflow

Library Number:
LITR134807219
Part Number:
720005054en
Author(s):
Paula Hong, John Van Antwerp, and Patricia McConville
Source:
Waters Corporation
Content Type:
Literature
Content Subtype:
White Papers

Historically, UV detection has been favored in many laboratories for its ease of use, robustness, and reliability. However, some of the inherent challenges include analytes that do not have a response in a UV channel, coelutions, and unknowns, any of which can require an orthogonal approach such as mass detection. While mass detection offers a number of benefits when used in tandem with UV detection, incorporating it into an existing UV workflow can be time-consuming and laborious.

Advances in both instrumentation and software now make mass detection a technique that is much more accessible to chromatographers working in pharmaceutical methods development. In this white paper, we describe the features of the ACQUITY QDa Detector and Empower 3 Software that have been purposefully designed to enable analysts to readily incorporate mass detection within a UV chromatographic workflow.


Title Format File Size
720005054en PDF 1631.67kB

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