Supercritical CO2 Based Technologies (SFx)
ACQUITY Advanced Polymer Chromatography (APC) System
Preparative Chromatography Solutions
Supercritical Fluid Chromatography
In this study, a trypsin digest of trastuzumab was used to demonstrate repeatability of a peptide mapping using the ACQUITY Arc Bio System.
The retention time percent RSD for 102 peptides ranged from 0.025–0.05% for the majority of peptides. The percent RSD for the area of eight peptides selected throughout the gradient ranged from 0.26–0.93%. The percent RSD for both metrics demonstrated excellent instrument precision, which is important for generating reliable data and providing confidence in results.
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