Waters offers a comprehensive range of analytical system solutions, software, and services for scientists. Liquid Chromatography. Mass Spectrometry. Waters is the leading provider of lab equipment, supplies and software for scientists across the world. Easily research and order everything your lab needs! Waters offers a comprehensive range of analytical system solutions, software, and services for scientists. Liquid Chromatography. Mass Spectrometry. Waters is the leading provider of lab equipment, supplies and software for scientists across the world. Easily research and order everything your lab needs!
Improved Analysis of Goldenseal Root Extract Using Charged Surface Hybrid (CSH) Column Technology
This application note demonstrates the use of charged surface hybrid (CSH) column technology which greatly improves loadability of alkaloids found in Goldenseal extract, when compared to a high purity, fully-porous C18 and superficially-porous C18 column. By improving sample loadability, the peak shape, resolution and sensitivity of detection of the alkaloids by UV is enhanced, facilitating identification of these componenets using a time-of-flight mass spectrometer (ToF-MS). The Goldenseal separation is then seamlessly transferred from UPLC to preparative HPLC using scalable CSH chemistries, alleviating the need to fully re-develop a preparative HPLC method for target compound purification.
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