Evaluation of the Performance of a Method for the Determination of Highly Polar, Anionic Pesticides in Foodstuffs Using LC-MS/MS
This application brief demonstrates the evaluation exercise that have shown the method to be a sensitive and reliable means for the determination of a series of different highly polar, anionic pesticides, and metabolites, using a combination of the QuPPe method, chromatography from the Waters Anionic Polar Pesticide (APP) Column and determination on Xevo TQ-S micro. The method allows for a fast and reliable quantitation down to concentrations well below typical MRLs and was successfully assessed according to the SANTE guidelines, presenting satisfactory results in cucumber, rice, soyabean, and milk. The procedure can also be applied to other commodities after suitable validation. This cost-effective method can be easily implemented in routine testing laboratories, and this evaluation shows the method may be suitable for checking compliance with MRLs and has the potential for screening at much lower concentrations, for example for food business operators’ due diligence testing.
