This Flyer demonstrates the combination of optimized chromatographic conditions, Waters Xevo TQ-S Cronos coupled with ACQUITY UPLC H-Class PLUS and ACQUITY UPLC BEH C18 Column produced robust method for quantification of N-nitroso morpholine impurity at method LOQ 0.03 ppm and the instrument shows excellent sensitivity with S/N ratio (>100) at 0.015 ppm level with respect to API.
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