A Robust and Sensitive Instrument for Quantification of N-nitroso Morpholine impurity in Mycophenolate Mofetil HCl Drug Product

Library Number:
LITR135116664
Author(s):
Waters
Source:
Waters
Content Type:
Literature
Content Subtype:
Brochures

This Flyer demonstrates the combination of optimized chromatographic conditions, Waters Xevo TQ-S Cronos coupled with ACQUITY UPLC H-Class PLUS and ACQUITY UPLC BEH C18 Column produced robust method for quantification of N-nitroso morpholine impurity at method LOQ 0.03 ppm and the instrument shows excellent sensitivity with S/N ratio (>100) at 0.015 ppm level with respect to API.


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