A Robust and Sensitive Instrument for Quantification of N-Nitroso Diethanolamine Impurity in Cholestyramine Drug Product

Library Number:
LITR135116683
Author(s):
Waters
Source:
Waters
Content Type:
Literature
Content Subtype:
Brochures

This flyer describes about optimized chromatographic conditions on Waters Xevo TQ-S Cronos coupled with ACQUITY UPLC H-Class PLUS & Symmetry C8 Column combination produced robust method for quantification N-Nitroso diethanolamineimpurity at method LOQ 0.09 ppm and the instrument shows excellent sensitivity with S/N ratio (>10) at 0.006 ppm level with respect to API.


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