This flyer describes about optimized chromatographic conditions on Waters Xevo TQ-S Cronos coupled with ACQUITY UPLC H-Class PLUS & Symmetry C8 Column combination produced robust method for quantification N-Nitroso diethanolamineimpurity at method LOQ 0.09 ppm and the instrument shows excellent sensitivity with S/N ratio (>10) at 0.006 ppm level with respect to API.
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