To overcome the analytical challenges of matrix effect and to improve the spiked recovery for N-Nitroso argatroban impurity in drug product needs a suitable sample preparation technique and chromatographic conditions. Waters Xevo TQ S Cronos coupled with ACQUITY UPLC H-Class PLUS and ACQUITY UPLC HSS T3 Column combination produced robust method for quantification.
Title | Format | File Size |
---|---|---|
Download PDF | 293.5kB |